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34358 Npc1a

34358

Npc1a

Niemann-Pick type C-1a

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition Niemann-Pick type C-1a

研究结论

Date Results Publications
2011-04-09 11:05:00 a sterol-dependent, ecdysone-independent mechanism of NPC1 function in Drosophila spermatogenesis. 21215267
2010-01-21 00:00:00 Mutations of a Drosophila NPC1 gene confer sterol and ecdysone metabolic defects 16079224
2010-01-21 00:00:00 dnpc1a function is crucial for normal steroid hormone metabolism 16221727
2010-01-21 00:00:00 The Niemann-Pick C proteins, in addition to their significant structural and sequence homology, these proteins may orchestrate their functions in a previously unappreciated fashion 17419988
2010-01-21 00:00:00 These data demonstrate a requirement for dNPC1a in the maintenance of neuronal function and viability and show that loss of dNPC1a in neurons mimics the human neurodegenerative condition. 18579730

名称对应

Type IDs
Synonymous CG5722, DmNPC, Dmel\CG5722, NPC1, NPC1a, Npc1, Npc1_Dm, dNPC1, dNPC1a, dmNPC1, dncp1a, dnpc1a, npc1, npc1a
Gene
UniProtKB-ID: X2J9B0_DROME, Q9VL24_DROME
UniprotKB: X2J9B0, Q9VL24
UniParc: UPI000007E9E6, UPI000358FDD4
EMBL: AE014134
EnsemblGenome: FBgn0024320
KO: dme:Dmel_CG5722
Nucleutide sequences
EMBL-CDS: AHN54311.1, AHN54310.1, AHN54309.1, ADV37019.1, ADV37021.1, AAF52874.2, ADV37020.1
Gene_ORFName: CG5722, Dmel_CG5722, CG5722, Dmel_CG5722
EnsemblGenome_TRS: FBtr0343609, FBtr0343610, FBtr0343608, FBtr0303905, FBtr0303906, FBtr0303907, FBtr0079957
Protein sequencees
EnsemblGenome_PRO: FBpp0310203, FBpp0310205, FBpp0310204, FBpp0292910, FBpp0292908, FBpp0292909, FBpp0079547
RefSeq: NP_001285795.1, NP_001285797.1, NP_001285796.1, NP_001188771.1, NP_001188769.1, NP_001188770.1, NP_609357.2
Others
UniRef100: UniRef100_X2J9B0, UniRef100_Q9VL24
UniRef90: UniRef90_Q9VL24
UniRef50: UniRef50_Q9VL24
UniGene: Dm.3071

全选

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