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Niemann-Pick C proteins in sterol transport and absorption: flies in the ointment.

Dev. Cell. 2007 Apr;12(4):481-3
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摘要


The Niemann-Pick C proteins have slowly emerged as regulators of subcellular lipid transport and sterol absorption at the small intestine. A recent article in Cell Metabolism suggests that in addition to their significant structural and sequence homology, these proteins may orchestrate their functions in a previously unappreciated fashion (Voght et al., 2007).

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