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3310 HSPA6

3310

HSPA6

heat shock protein family A (Hsp70) member 6

protein-coding

Homo sapiens

基因描述

Type Description
Definition heat shock protein family A (Hsp70) member 6

研究结论

Date Results Publications
2019-03-30 11:37:00 is a cigarette smoke-induced ulcerative colitis (UC)-susceptibility gene. The Hduanyu18426 risk locus is associated with decreased Hduanyu18426 expression. Hduanyu18426 provides epithelial protection by stabilizing anti-apoptotic Bcl-XL, thereby contributing to the beneficial effect of cigarette smoking in UC. 26826017
2018-08-18 12:10:00 that and contribute to protection of differentiated human neuronal cells from cellular stress 29090408
2018-03-03 10:41:00 during recovery from neuronal stress, localized with perispeckles that have been characterized as transcription sites; the stress-induced association of Hduanyu18426 with perispeckles displayed the greatest dynamism compared to the interaction of Hduanyu18426 or with other stress-sensitive cytoplasmic and nuclear structures; this suggests involvement of Hduanyu18426 in recovery of neurons from cellular stress 27527722
2018-02-24 11:57:00 In vivo efficacy experiments with siRNA and MFH were performed using the A2780cp20 and HeyA8 ovarian cancer mouse models. A significantly reduction in tumor growth rate was observed with combination therapy. PES and MFH efficacy were also evaluated in the HeyA8 intraperitoneal tumor model, and resulted in robust antitumor effects. 28223424
2018-01-06 11:57:00 measurable HSP70B' was not associated with graft versus host disease following allogeneic hematopoietic cell transplantation 27020764

名称对应

Type IDs
Synonymous HSP70B'
Gene
UniProtKB-ID: HSP76_HUMAN, B3KSM6_HUMAN, A0A384NKX5_HUMAN
UniprotKB: P17066, B3KSM6, A0A384NKX5
UniParc: UPI00003728EF, UPI0000074238
EMBL: X51757, GQ891451, BC035665, BC004279, AL590385, AK093925, DQ521571, X51758, S78631
Ensembl: ENSG00000173110
KO: hsa:3310
Nucleutide sequences
EMBL-CDS: ABF47108.1, CAA36062.1, AAH35665.1, CAA36061.1, AAH04279.1, BAG52788.1, ADO22313.1
Ensembl_TRS: ENST00000309758
Protein sequencees
Ensembl_PRO: ENSP00000310219
RefSeq: NP_002146.2
Others
UniRef100: UniRef100_P17066, UniRef100_B3KSM6
UniRef90: UniRef90_P17066
UniRef50: UniRef50_P17066
UniGene: Hs.654614
CCDS: CCDS1231.1

全选

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