| Type | Description |
|---|---|
| Definition | RNA polymerase II 215kD subunit |
| Date | Results | Publications |
|---|---|---|
| 2020-09-19 15:54:00 | The C-terminal domain (CTD) of RNA polymerase II (Pol II) is composed of repeats of the consensus YSPTSPS and is an essential binding scaffold for transcription-associated factors, supporting drosophila development with consensus heptads. | 30765194 |
| 2018-08-04 10:51:00 | Study measured the first wave of de novo transcription in living Drosophila embryos using dual-fluorescence detection of nascent transcripts containing 5' MS2 and 3' PP7 RNA stem loops. Pol II elongation rates of 2.4-3.0 kb/min were observed, approximately twice as fast as earlier estimates | 28457866 |
| 2017-05-20 12:46:00 | Genetic and biochemical analyses reveal a functional interaction of MSL1 with CDK7, a subunit of the Cdk-activating kinase (CAK) complex of the general transcription factor TFIIH. Importantly, MSL1 depletion leads to decreased phosphorylation of Ser5 of RNA polymerase II. | 27183194 |
| 2017-02-25 12:01:00 | Phosphorylation of the C-terminal domain of RNA polymerase II (CTD) plays an essential role in eukaryotic transcription by recruiting transcriptional regulatory factors to the active polymerase. This study shows that Tyrosine 1 is required for CTD phosphorylation by Erk2. | 28103682 |
| 2016-01-25 08:36:00 | Study provides additional evidence that Zeste protein plays no role in the activation of the white gene transcription; does not rule out that the white gene enhancer is able to recruit RNAPII and function as a weak promoter | 25937222 |
| Type | IDs |
|---|---|
| Synonymous | 5, 8WG16, CG1554, CTD, Dmel\CG1554, H5, II, IIo, L5, POL, Pol II, Pol II CTD, Pol II Ser5P, Pol II Ser5p, Pol II0[ser2], Pol II0[ser5], Pol II[ser2], Pol IIa, Pol IIo, Pol IIo[Ser2], Pol IIo[ser2], Pol IIo[ser5], Pol-II, Pol-IIa, PolII, PolIIa, PolIIo, PolIIo[ser2], PolIIo[ser5], Poll II, RNA Pol II, RNA Pol II CTD, RNA PolI 215, RNA PolII, RNA pol II, RNA pol IIo, RNA polII, RNA-Pol, RNA-PolII, RNAP, RNAP II, RNAP II LS, RNAPII, RNAPII0, RNApol, RNApol2, RNApolII, RPB1, RPII215, RpII, Rpb1, Rpll215, Ser5-P Pol II, Ubl, alphaPol IIo[ser2], dRPB1, dRpb1, l(1)10Ca, l(1)DC912, l(1)DF912, l(1)G0040, l(1)L5, pol II, polII, rpII1 |
| Gene |
UniProtKB-ID:
RPB1_DROME,
D0Z769_DROME
UniprotKB:
P04052,
D0Z769
UniParc:
UPI0000124CBB
EMBL:
BT100316,
M27431,
AE014298,
M14203,
M19537,
M11798
EnsemblGenome:
FBgn0003277
KO:
dme:Dmel_CG1554
|
| Nucleutide sequences |
EMBL-CDS:
AAA28827.1,
AAA28863.1,
AAF48057.1,
AAA28868.1,
AAA28864.1,
ACZ54678.1
Gene_ORFName:
CG1554
EnsemblGenome_TRS:
FBtr0073542,
FBtr0073542
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0073387,
FBpp0073387
RefSeq:
NP_511124.1
|
| Others |
UniRef100:
UniRef100_P04052
UniRef90:
UniRef90_P04052
UniRef50:
UniRef50_P04052
UniGene:
Dm.2925
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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