| Type | Description |
|---|---|
| Definition | Thioredoxin reductase-1 |
| Date | Results | Publications |
|---|---|---|
| 2017-12-02 11:18:00 | Overexpression of mitochondrial TXNRD2 in Drosophila melanogaster extended median lifespan in female flies with a small lifespan extension in males; in contrast, overexpression of the cytosolic form, TXNRD1, did not produce a lifespan extension. | 28474396 |
| 2011-08-13 10:21:00 | Molecular orbital calculations suggested that the C-terminal hexapeptide Pro-Ala-Ser-Cys-Cys-Ser-OH functions as a redox center that alleviates the necessity for selenium in Dm-TrxR. | 21389620 |
| 2010-01-21 00:00:00 | analysis of the mechanism of high Mr thioredoxin reductase from Drosophila melanogaster | 12816954 |
| 2010-01-21 00:00:00 | X-ray crystal structure of thioredoxin reductase at 2.4 A resolution; demonstrated that tetrapeptides equivalent to the oxidized C-terminal active sites of both mouse mitochondrial TR (mTR3) and DmTR are substrates for the truncated forms of both enzymes | 17385893 |
| 2010-01-21 00:00:00 | the role of Glu-469' in catalysis by DmTrxR | 18991392 |
| Type | IDs |
|---|---|
| Synonymous | 2151, CG2151, DTR, Dm-TrxR, DmTR, DmTrx, DmTrxR, DmTrxR-1, Dmel\CG2151, GR, Gr, TH, TRR, TRXR1, Trx, TrxR, TrxR-1, Trxr, Trxr1, anon-WO03040301.185, anon-WO03040301.187, dTrxR, dmtrxr-1, gr, l(1)G0154, l(1)G0379, l(1)G0477, l(1)G0481, trxr-1 |
| Gene |
UniProtKB-ID:
TRXR1_DROME
UniprotKB:
P91938
UniParc:
UPI000002B649,
UPI000000BF7E,
UPI00001376D7,
UPI0000124D17
EMBL:
AF301144,
AE014298,
AF301145,
BT003266,
BT025070,
U81995,
AY051643
EnsemblGenome:
FBgn0020653
KO:
dme:Dmel_CG2151
|
| Nucleutide sequences |
EMBL-CDS:
AAN09228.1,
AAF46354.1,
ABE73241.1,
AAB48441.1,
AAK93067.1,
AAG25639.1,
AAO25023.1,
AAG25640.1,
AAF46355.2
Gene_ORFName:
CG2151
EnsemblGenome_TRS:
FBtr0071169,
FBtr0071168,
FBtr0071167
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0071117,
FBpp0071115,
FBpp0071116
RefSeq:
NP_727252.1,
NP_727251.1,
NP_511082.2,
NP_001368975.1
|
| Others |
UniRef100:
UniRef100_P91938
UniRef90:
UniRef90_P91938
UniRef50:
UniRef50_P91938
UniGene:
Dm.20991
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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