| Type | Description |
|---|---|
| Definition | aldehyde oxidase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-12 13:23:00 | Epigenetic loss of AOX1 expression via EZH2 leads to metabolic deregulations and promotes bladder cancer progression. | 31383940 |
| 2020-07-11 10:41:00 | Study utilized a collection of computational tools with concordance analysis approaches to predict putative phenotypic effects and protein stability changes of all validated hAOX1 nonsynonymous single nucleotide polymorphisms (nsSNPs) deposited in the dbSNP. Study constitutes the first extensive analysis for the presence of nsSNPs in hAOX1. | 31768259 |
| 2020-02-29 11:40:00 | This prospective study aimed to evaluate the effects of genetic polymorphisms in sulindac-related metabolizing enzyme genes including FMO3 and AOX1 on the population pharmacokinetics of sulindac in 58 pregnant women with preterm labor | 31993760 |
| 2019-11-16 12:15:00 | In this study, the authors present the crystal structure of the inactive variant G1269R, revealing the first structure of a molybdenum cofactor (Moco)-free form of hAOX1. These data allowed to model, for the first time, the flexible Gate 1 that controls access to the active site. | 30985987 |
| 2019-07-06 12:02:00 | substrate selectivity of human AOX1 for the reduction of nitroaromatic drugs | 30367827 |
| Type | IDs |
|---|---|
| Synonymous | AO, AOH1 |
| Gene |
UniProtKB-ID:
AOXA_HUMAN
UniprotKB:
Q06278
UniParc:
UPI0000071863
EMBL:
AF009471,
AC007163,
AF009463,
AF009470,
BC117179,
AF009473,
AF009459,
AF009446,
AF009469,
AF009452,
AF009453,
AF009442,
AF009444,
AF009457,
AF009449,
AF009448,
AF009450,
AC080164,
AF009460,
AF009461,
BC117181,
AF009466,
AF009465,
AF009441,
AF010260,
AF009455,
AF009472,
L11005,
AF009454,
CH471063,
AF009462,
AF017060,
AF009447,
AF009464,
AF009474,
AF009456,
AF009445,
AF009467,
AF009451,
AF009443,
AB046692,
AF009468,
AF009458
Ensembl:
ENSG00000138356
KO:
hsa:316
|
| Nucleutide sequences |
EMBL-CDS:
AAB83968.1,
AAI17180.1,
AAY24265.1,
AAB83966.1,
EAW70209.1,
AAA96650.1,
BAB40305.1,
AAI17182.1,
AAX93285.1
Ensembl_TRS:
ENST00000374700
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000363832
RefSeq:
NP_001150.3,
XP_016859435.1,
XP_011509364.1,
XP_016859436.1
|
| Others |
UniRef100:
UniRef100_Q06278
UniRef90:
UniRef90_Q06278
UniRef50:
UniRef50_Q06278
UniGene:
Hs.406238
CCDS:
CCDS33360.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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