| Type | Description |
|---|---|
| Definition | ADP ribosylation factor guanine nucleotide exchange factor 1 |
| Date | Results | Publications |
|---|---|---|
| 2015-02-28 12:10:00 | Overexpression of BIG1 in neurites significantly increases ERK phosphorylation. | 24090963 |
| 2014-11-22 11:15:00 | A role was identified for BIG1 in modulating GABA-gated Cl(-) influx through regulation of GABA A receptor expression. | 24198228 |
| 2013-03-16 11:48:00 | BIG1, through its ability to activate ADP-ribosylation factor 1, regulates cell-surface levels and function of ABCA1. | 23220274 |
| 2010-01-21 00:00:00 | myosin IXb binds to BIG1, which regulates its Rho-GTPase activating protein activity [BIG1] | 15644318 |
| Type | IDs |
|---|---|
| Synonymous | BIG1, RGD1560793 |
| Gene |
UniProtKB-ID:
BIG1_RAT
UniprotKB:
D4A631
UniParc:
UPI0000506BB8
EMBL:
CH473984
Ensembl:
ENSRNOG00000005703
KO:
rno:312915
|
| Nucleutide sequences |
EMBL-CDS:
EDM11544.1
Ensembl_TRS:
ENSRNOT00000007766
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000007766
RefSeq:
NP_001263985.1,
XP_017448811.1
|
| Others |
UniRef100:
UniRef100_D4A631
UniRef90:
UniRef90_D4A631
UniRef50:
UniRef50_Q9Y6D6
UniGene:
Rn.6834
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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