| Type | Description |
|---|---|
| Definition | enhancer of zeste 2 polycomb repressive complex 2 subunit |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:16:00 | Ezh2-dependent H3K27me3 modification dynamically regulates vitamin D3-dependent epigenetic control of CYP24A1 gene expression in osteoblastic cells. | 31907922 |
| 2021-02-20 13:30:00 | Inhibition of EZH2 (Enhancer of Zeste Homolog 2) Attenuates Neuroinflammation via H3k27me3/SOCS3/TRAF6/NF-kappaB (Trimethylation of Histone 3 Lysine 27/Suppressor of Cytokine Signaling Receptor Family 6/Nuclear Factor-kappaB) in a Rat Model of Subarachnoid Hemorrhage. | 32933418 |
| 2020-08-15 16:04:00 | Pb exposure diminished H3K27me3 levels in vivo by suppressing EZH2 (enhancer of zeste homolog 2) expression at an early stage. Furthermore, miR-137 and EZH2 constitute mutually inhibitory loop to regulate the H3K27me3 level, and this feedback regulation could be specifically activated by Pb treatment. | 31511494 |
| 2020-07-25 10:19:00 | High EZH2 expression is associated with neuropathic pain. | 30390343 |
| 2020-06-06 11:57:00 | We found abundant GAS5 expression and a reduction in RGC density in the retinal tissues of glaucoma rats. Silencing of GAS5 led to increased EZH2 expression and decreased ABCA1 expression in RGCs. In addition, upregulation of EZH2 promoted trimethylation of lysine 27 on histone H3, thereby suppressing ABCA1 expression and eventually leading to the inhibition of RGC apoptosis. | 31608710 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
B5DFE2_RAT
UniprotKB:
B5DFE2
UniParc:
UPI0000182BDD
EMBL:
AABR07060512,
BC169027,
CH473959
Ensembl:
ENSRNOG00000006048
KO:
rno:312299
|
| Nucleutide sequences |
EMBL-CDS:
AAI69027.1,
EDM15557.1
Gene_ORFName:
rCG_28121
Ensembl_TRS:
ENSRNOT00000008149
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000008149
RefSeq:
XP_006236463.1,
XP_008761106.1,
XP_006236466.1,
XP_006236468.1,
XP_006236464.1,
XP_006236470.1,
NP_001128451.1,
XP_006236465.1,
XP_006236467.1
|
| Others |
UniRef100:
UniRef100_B5DFE2
UniRef90:
UniRef90_B5DFE2
UniRef50:
UniRef50_P70351
UniGene:
Rn.9027
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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