| Type | Description |
|---|---|
| Definition | BCR, RhoGEF and GTPase activating protein |
| Date | Results | Publications |
|---|---|---|
| 2018-01-06 12:29:00 | This work identifies BCR as a critical player in Rac1 regulation during oxygen and glucose deprivation in hippocampal neurons. | 29046349 |
| 2015-04-25 12:17:00 | Data indicate that Src homology 2 domain containing protein 5 (SH2D5) controls neuronal morphology via breakpoint cluster region protein BCR and Rac1 GTP binding protein. | 25331951 |
| 2013-04-27 10:39:00 | BCR is a novel substrate of PTPRT . | 22767509 |
| 2012-06-02 11:34:00 | these data identify UAP56 as an important binding partner of Bcr and a novel target for inhibiting vascular smooth muscle cell proliferation. | 22446327 |
| 2010-11-27 10:45:00 | BCR and active BCR-related gene have novel roles in the regulation of synaptic Rac1 signaling, synaptic plasticity, and learning and memory, and that excessive Rac1 activity negatively affects synaptic and cognitive functions | 20962234 |
| Type | IDs |
|---|---|
| Gene | |
| Nucleutide sequences | |
| Protein sequencees |
RefSeq:
XP_006223946.1,
XP_017457374.1
|
| Others |
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 29046349 |
J Biol Chem Katharine R Smith , Dipen Rajgor , Jonathan G Hanley |
2017-12-08 | - |
| 25763846 |
Seizures are regulated by ubiquitin-specific peptidase 9 X-linked (USP9X), a de-ubiquitinase. PLoS Genet. Lily Paemka , Vinit B Mahajan , Salleh N Ehaideb , Jessica M Skeie , Men Chee Tan , Shu Wu , Allison J Cox , Levi P Sowers , Jozef Gecz , Lachlan Jolly , Polly J Ferguson , Benjamin Darbro , Amy Schneider , Ingrid E Scheffer , Gemma L Carvill , Heather C Mefford , Hatem El-Shanti , Stephen A Wood , J Robert Manak , Alexander G Bassuk |
2015-03-01 | - |
| 25331951 |
J Biol Chem Elizabeth J Gray , Evangelia Petsalaki , D Andrew James , Richard D Bagshaw , Melissa M Stacey , Oliver Rocks , Anne-Claude Gingras , Tony Pawson |
2014-12-19 | - |
| 25049327 |
J. Clin. Oncol. Kathryn G Roberts , Deqing Pei , Dario Campana , Debbie Payne-Turner , Yongjin Li , Cheng Cheng , John T Sandlund , Sima Jeha , John Easton , Jared Becksfort , Jinghui Zhang , Elaine Coustan-Smith , Susana C Raimondi , Wing H Leung , Mary V Relling , William E Evans , James R Downing , Charles G Mullighan , Ching-Hon Pui |
2014-09-20 |
Bcr,
Abl1
|
| 25133686 |
PLoS ONE Jin Cai , Gengze Wu , Xiaorong Tan , Yu Han , Caiyu Chen , Chuanwei Li , Na Wang , Xue Zou , Xinjian Chen , Faying Zhou , Duofen He , Lin Zhou , Pedro A Jose , Chunyu Zeng |
2014-01-01 | - |
| 23940119 |
The GEF Bcr activates RhoA/MAL signaling to promote keratinocyte differentiation via desmoglein-1. J. Cell Biol. Adi D Dubash , Jennifer L Koetsier , Evangeline V Amargo , Nicole A Najor , Robert M Harmon , Kathleen J Green |
2013-08-19 |
DSG1,
RHOA,
MAL,
BCR
|
| 23382219 |
Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins. Proc. Natl. Acad. Sci. U.S.A. Rajesh Ghai , Andrea Bugarcic , Huadong Liu , Suzanne J Norwood , Sune Skeldal , Elizabeth J Coulson , Shawn Shun-Cheng Li , Rohan D Teasdale , Brett M Collins |
2013-02-19 |
Nt5dc3,
Grm7,
Olr1,
Bcr,
Nr3c2,
Adgrv1,
Adcyap1r1,
Adrb2,
Alk,
App,
Ddr1,
Cr2,
Cr1l,
Egfr,
Erbb2,
Erbb3,
Erbb4,
Fgfr1,
Flt1,
Flt4,
Lrp2,
Gpr37,
Hras,
Igf1r,
Il4ra,
Insr,
Itga3,
Itgb1,
Itgb2,
Itgb3,
Itgb5,
Itgb6,
Itgb7,
Itln1,
Itpr2,
Itpr3,
Ldlr,
Lepr,
Lrp1,
Lrp8,
Tlr7,
Gpr37l1,
Mttp,
Notch1,
Notch2,
Notch3,
Nppb,
Npr1,
Musk,
Ntrk1,
Ntrk2,
Ntrk3,
Pigr,
Pla2r1,
Ptpra,
Ptprb,
Ptprn2,
Itgb4,
Ret,
Selp,
Il23r,
Tnfrsf1a,
Trpc1,
Tshr,
Vipr1,
Vldlr,
Impg2,
P2rx3,
Gpr61,
P2rx2,
Gpr119,
Amfr,
Insrr,
Gpr20,
Gpr101,
Trpv3,
Ror1,
Snx17,
Fcrl5,
Taok2,
Gpr62,
Gabrq,
Cd200r1,
Pex5l,
Snx31,
Loxl4,
Rnmt,
Gprc5c,
Gpr160,
Plxdc1,
Tm7sf2,
Slitrk5,
Snx27,
Gpr84,
Gpr63,
Tas1r2,
Mcoln1,
Lrp1b,
ADCYAP1R1
|
| 22767509 |
Regulation of dendritic arborization by BCR Rac1 GTPase-activating protein, a substrate of PTPRT. J. Cell. Sci. A-Reum Park , Daeyoung Oh , So-Hee Lim , Jeonghoon Choi , Jeonghee Moon , Dae-Yeol Yu , Sung Goo Park , Nora Heisterkamp , Eunjoon Kim , Pyung-Keun Myung , Jae-Ran Lee |
2012-10-01 |
Bcr,
Ptprt,
Bcr,
Ptprt
|
| 22446327 |
UAP56 is a novel interacting partner of Bcr in regulating vascular smooth muscle cell DNA synthesis. Biochem. Biophys. Res. Commun. Abha Sahni , Nadan Wang , Jeffrey D Alexis |
2012-04-13 |
Ddx39b,
Bcr,
DDX39B
|
| 23152932 |
Lack of bcr and abr promotes hypoxia-induced pulmonary hypertension in mice. PLoS One Min Yu , Dapeng Gong , Min Lim , Anna Arutyunyan , John Groffen , Nora Heisterkamp |
2012-01-01 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
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| 排名 | 研究人员 | 文献 |
|---|---|---|
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