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30923 Foxe3

30923

Foxe3

forkhead box E3

protein-coding

Mus musculus

基因描述

Type Description
Definition forkhead box E3

研究结论

Date Results Publications
2018-02-17 10:48:00 These results clearly show that the development of early-onset cataracts requires at least two mutant alleles of Foxe3(rct) and Pde6b(rd1), and another modifier associated with the severity of cataract phenotypes in Foxe3(rct) mice underlies the genetic backgrounds in mice. 29317205
2015-06-20 11:28:00 The Hedgehog pathway with its member Smoothened is required during a discrete embryonic period (E9.5-E12.5) in lens development to regulate lens epithelial cell proliferation, survival and FoxE3 expression. 25268479
2014-09-06 11:28:00 Foxe3 as a transcriptional target of Pitx3 explains at least in part some of the phenotypic similarities of the ak and dyl mice (dysgenic lens, a Foxe3 allele). 24307298
2012-09-01 10:19:00 The observed changes in the expression of FoxE3 suggest that Msx2 is an important contributor in controlling transcription of target genes critical for early eye development. 22503753
2012-08-18 10:18:00 the ectopic activation of downstream effectors of the hedgehog signaling pathway in the mouse lens disrupts normal fiber cell differentiation by a mechanism consistent with a sustained epithelial cellular developmental program driven by FoxE3. 22491411

名称对应

Type IDs
Synonymous FREAC8, dyl, rct
Gene
UniProtKB-ID: FOXE3_MOUSE
UniprotKB: Q9QY14
UniParc: UPI000002460C
EMBL: AF142647
Ensembl: ENSMUSG00000044518
KO: mmu:30923
Nucleutide sequences
EMBL-CDS: AAF15997.1
Ensembl_TRS: ENSMUST00000050940
Protein sequencees
Ensembl_PRO: ENSMUSP00000050445
RefSeq: NP_056573.1
Others
UniRef100: UniRef100_Q9QY14
UniRef90: UniRef90_Q9QY14
UniRef50: UniRef50_Q9QY14
UniGene: Mm.377122
CCDS: CCDS18483.1

全选

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研究热度

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