| Type | Description |
|---|---|
| Definition | CXXC finger protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-12-29 11:25:00 | CFP1 binds open chromatin regions of active genes, including enhancers and non-CpG islands. | 30292235 |
| 2018-09-22 10:11:00 | directly controls the expression of key genes important for thymocyte survival, such as RORgammat, and for T-cell receptor signaling, including Zap70 and CD8, through maintaining the appropriate H3K4me3 on their promoters | 27210293 |
| 2014-03-22 11:07:00 | NF-kappaB recruitment enhanced the occupancy of the CpG island within the 14-3-3gamma promoter by CFP1.14-3-3gamma induction in CSR is enabled by the CFP1-mediated H3K4me3 enrichment in the promoter, dependent on NF-kappaB and sustained by E2A. | 23851690 |
| 2011-08-06 11:02:00 | The crescent-shaped CFP1 CXXC domain is wedged into the major groove of the CpG DNA, distorting the B-form DNA, and interacts extensively with the major groove of the DNA. | 21407193 |
| 2010-01-21 00:00:00 | study shows endogenous DNMT1 & CFP1 interact in vivo; CFP1 interaction with Setd1A or Setd1B not required for its interaction with DNMT1; result indicates CFP1 intersects cytosine methylation machinery independently of its association with Setd1 complexes | 18680430 |
| Type | IDs |
|---|---|
| Synonymous | 2410002I16Rik, 5830420C16Rik, CFP1, CGBP, HsT2645, PCCX1, PHF18, SPP1, ZCGPC1, hCGBP |
| Gene |
UniProtKB-ID:
CXXC1_HUMAN
UniprotKB:
Q9P0U4
UniParc:
UPI0000169F65,
UPI0000037D2E
EMBL:
AL136862,
BC029922,
BC014940,
AF149758,
BC015733,
AK314886,
AB031069,
AC090246
Ensembl:
ENSG00000154832
KO:
hsa:30827
|
| Nucleutide sequences |
EMBL-CDS:
AAH14940.1,
BAA96307.1,
AAH15733.1,
AAF37799.1,
CAB66796.1,
BAG37400.1,
AAH29922.1
Ensembl_TRS:
ENST00000285106,
ENST00000412036
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000390475,
ENSP00000285106
RefSeq:
NP_055408.2,
XP_011524243.1,
XP_016881207.1,
NP_001095124.1,
XP_016881208.1,
XP_011524242.1
|
| Others |
UniRef100:
UniRef100_Q9P0U4
UniRef90:
UniRef90_Q9P0U4
UniRef50:
UniRef50_Q9P0U4
UniGene:
Hs.180933
CCDS:
CCDS45866.1,
CCDS11945.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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