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30819 KCNIP2

30819

KCNIP2

potassium voltage-gated channel interacting protein 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition potassium voltage-gated channel interacting protein 2

研究结论

Date Results Publications
2020-07-18 12:11:00 The palmitoylation status of KChIP2 determines its subcellular distribution in cardiac myocytes. Stress promotes nuclear entry of KChIP2, diverting it from ion channel modulation at the plasma membrane to other functions in the nuclear compartment. 31362018
2019-05-25 10:46:00 polybasic motif in alternatively spliced KChIP2 isoforms prevents Ca(2+) regulation of Kv4 channels 30622142
2019-02-23 10:48:00 Binding of Ca(2+) to KChIP2 EF-hands can acutely modulate Kv4.3/KChIP2 channel inactivation gating. 28735419
2018-05-12 12:10:00 although there is a baseline presence of KChIP2 in the nucleus both in vivo and in vitro, KChIP2 does not directly regulate transcriptional activity. Moreover, the nuclear transport of KChIP2 is not dependent on Ca(2+). Thus, KChIP2 does not function as a conventional transcription factor in the heart. 27349185
2018-03-17 11:00:00 Our results do not support the notion that accessory KChIP2 binding is a prerequisite for dendritic trafficking and functional surface expression of Kv4.2 channels, however, accessory KChIP2 binding may play a potential role in Kv4.2 modulation during intrinsic plasticity processes. 29385176

名称对应

Type IDs
Synonymous KCHIP2
Gene
UniProtKB-ID: KCIP2_HUMAN, B3KSZ5_HUMAN, A0A2R8Y6D7_HUMAN
UniprotKB: Q9NS61, B3KSZ5, A0A2R8Y6D7
UniParc: UPI000006D31D, UPI000006EEFD, UPI000004A277, UPI000004A260, UPI0000E22662, UPI000004A262, UPI0000070A70, UPI000006FE6F, UPI00003E5E0E, UPI000004A25E, UPI0000576814
EMBL: AL136722, AY026328, AF367018, BC034685, DQ148481, AF367019, AK315042, AF295076, CH471066, AC010789, AF367020, AJ276317, AB044584, AY302141, AF347114, AF199598, AF295530, DQ148480, AY026331, AK094668, DQ148483, AY026330, AY026329, AB044585, AK027347, AF367021
Ensembl: ENSG00000120049
KO: hsa:30819
Nucleutide sequences
EMBL-CDS: AAK53710.1, AAZ77798.1, BAB55052.1, AAH34685.1, BAG37523.1, AAZ77800.1, AAP57633.1, AAG02121.1, AAG02120.1, AAK53709.1, CAB77054.1, CAB66656.1, AAK07674.1, BAA96740.1, EAW49733.1, AAK53707.1, AAF33683.1, AAK53708.1, AAK21972.1, AAK70356.1, AAZ77797.1, BAA96741.1, BAG52907.1
Ensembl_TRS: ENST00000353068, ENST00000356640, ENST00000343195, ENST00000358038, ENST00000348850, ENST00000461105, ENST00000239117, ENST00000434163, ENST00000642874
Protein sequencees
Ensembl_PRO: ENSP00000350733, ENSP00000341624, ENSP00000349055, ENSP00000344169, ENSP00000239117, ENSP00000239118, ENSP00000420040, ENSP00000411679, ENSP00000495474
RefSeq: XP_016871650.1, NP_775287.1, NP_775285.1, NP_775286.1, XP_006717875.1, NP_775284.1, NP_775289.1, XP_005269786.1, XP_011538033.1, NP_055406.2, NP_775283.1, XP_005269787.1
Others
UniRef100: UniRef100_Q9NS61, UniRef100_A0A2R8Y6D7, UniRef100_B3KSZ5
UniRef90: UniRef90_A0A2R8Y6D7, UniRef90_F7AWN8, UniRef90_Q9NS61
UniRef50: UniRef50_Q9NS61, UniRef50_M3YZM7, UniRef50_D5LL09
UniGene: Hs.97044
CCDS: CCDS7522.1, CCDS41562.1, CCDS7523.1, CCDS7525.1, CCDS7521.1, CCDS7526.1, CCDS7524.1

全选

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