Type | Description |
---|---|
Definition | PDZ and LIM domain 4 |
Date | Results | Publications |
---|---|---|
2020-06-20 11:06:00 | findings have identified Pdlim4 as a JMJD3 target gene that affects T-cell trafficking by cooperating with S1P1, and provided insights into the molecular mechanisms by which JMJD3 regulates genes involved in T cell trafficking. | 31393857 |
2020-06-06 13:58:00 | Pdlim4 is required for dendritic cell migration via CCR7-JNK, dendrite formation, and subsequent development of functional T-cell responses. | 31287961 |
2010-01-21 00:00:00 | PDLIM4 may function as a tumor suppressor, involved in the control of cell proliferation by associating with actin in prostate cancer cells. | 19212833 |
2010-01-21 00:00:00 | RIL C-terminus proper, but not the RIL LIM domain, can interact with protein tyrosine phosphatase BL | 15663004 |
Type | IDs |
---|---|
Synonymous | Ril |
Gene |
UniProtKB-ID:
PDLI4_MOUSE,
Q5SWV3_MOUSE
UniprotKB:
P70271,
Q5SWV3
UniParc:
UPI000002160C,
UPI000047048B
EMBL:
Y08361,
BC030068,
CH466575,
AL596444
Ensembl:
ENSMUSG00000020388
KO:
mmu:30794
|
Nucleutide sequences |
EMBL-CDS:
AAH30068.1,
CAA69648.1,
EDL33550.1
Ensembl_TRS:
ENSMUST00000018755,
ENSMUST00000093109
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000018755,
ENSMUSP00000090797
RefSeq:
NP_062290.2,
XP_030101927.1,
XP_006533574.1
|
Others |
UniRef100:
UniRef100_P70271,
UniRef100_Q5SWV3
UniRef90:
UniRef90_Q5SWV3,
UniRef90_P70271
UniRef50:
UniRef50_P70271,
UniRef50_A0A2K6EFU4
UniGene:
Mm.21830
CCDS:
CCDS24690.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
---|---|---|---|
32325033 |
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Cell Syst Reza Pourhaghighi , Peter E A Ash , Sadhna Phanse , Florian Goebels , Lucas Z M Hu , Siwei Chen , Yingying Zhang , Shayne D Wierbowski , Samantha Boudeau , Mohamed T Moutaoufik , Ramy H Malty , Edyta Malolepsza , Kalliopi Tsafou , Aparna Nathan , Graham Cromar , Hongbo Guo , Ali Al Abdullatif , Daniel J Apicco , Lindsay A Becker , Aaron D Gitler , Stefan M Pulst , Ahmed Youssef , Ryan Hekman , Pierre C Havugimana , Carl A White , Benjamin C Blum , Antonia Ratti , Camron D Bryant , John Parkinson , Kasper Lage , Mohan Babu , Haiyuan Yu , Gary D Bader , Benjamin Wolozin , Andrew Emili |
2020-04-22 | - |
31287961 |
FASEB J. Ji-Young Yoo , Nam-Chul Jung , Jun-Ho Lee , So-Yeon Choi , Hyun-Ji Choi , Soo-Yeoun Park , Ji-Su Jang , Sei-Hee Byun , Sung-Uk Hwang , Kyung-Eun Noh , Yunok Park , Jongwon Lee , Jie-Young Song , Han Geuk Seo , Hyun Soo Lee , Dae-Seog Lim |
2019-10-01 | - |
31393857 |
JMJD3 regulates CD4 T cell trafficking by targeting actin cytoskeleton regulatory gene Pdlim4. J. Clin. Invest. Chuntang Fu , Qingtian Li , Jia Zou , Changsheng Xing , Mei Luo , Bingnan Yin , Junjun Chu , Jiaming Yu , Xin Liu , Helen Y Wang , Rong-Fu Wang |
2019-08-08 | - |
24154525 |
Development Jeremy A Miller , Jason Nathanson , Daniel Franjic , Sungbo Shim , Rachel A Dalley , Sheila Shapouri , Kimberly A Smith , Susan M Sunkin , Amy Bernard , Jeffrey L Bennett , Chang-Kyu Lee , Michael J Hawrylycz , Allan R Jones , David G Amaral , Nenad Å estan , Fred H Gage , Ed S Lein |
2013-11-01 |
Rpp25,
Gldc,
Rhoq,
Psat1,
Tm6sf1,
Slc14a1,
Rimklb,
Nusap1,
Mybpc1,
Npy,
Bmp3,
Adgrv1,
Dlx1as,
Acadl,
Laptm4b,
Pawr,
Adra1a,
Alcam,
Aldoc,
Necab2,
Ank1,
Apoe,
Nr2f2,
Aqp4,
Rnd2,
Arnt2,
Bcan,
Bcat1,
Fabp7,
Zfp36l1,
C1qc,
Calb2,
Capn2,
Car2,
Cbln2,
Cbs,
Ccnd2,
Cd24a,
Entpd2,
Cd63,
Cd81,
Cd9,
Cdh11,
Cdh5,
Cit,
Ckb,
Cldn5,
Clu,
Cnp,
Cnr1,
Col19a1,
Col9a3,
Cort,
Cox6a2,
Cplx1,
Hapln1,
Cryab,
Csrp1,
Cst3,
Ctsd,
Ctsl,
Ctss,
Cux2,
Dbi,
Dcx,
Asap1,
Dio2,
Dlx1,
Cdk2ap1,
Ect2,
Egfr,
Eps8,
Erbb4,
Eya4,
Elmo1,
Fasn,
Fgf12,
Fgfr1,
Gaa,
Gabrg3,
Gad1,
Gad2,
Gap43,
Gfap,
Gpr83,
Gja1,
Gjd2,
Glul,
Glrb,
Gnai1,
Gnas,
Got1,
Adgrg1,
Cdca3,
Gria4,
Grik1,
Grpr,
Hbb-b1,
Hbb-b2
|
23341629 |
Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proc. Natl. Acad. Sci. U.S.A. Stephen Lumayag , Caroline E Haldin , Nicola J Corbett , Karl J Wahlin , Colleen Cowan , Sanja Turturro , Peter E Larsen , Beatrix Kovacs , P Dane Witmer , David Valle , Donald J Zack , Daniel A Nicholson , Shunbin Xu |
2013-02-05 |
Mthfsl,
Ildr2,
Copg2os2,
Rell1,
Lrrc8c,
Mirc35hg,
Meig1,
Mbnl2,
Mthfs,
Galnt7,
Lmo1,
Cald1,
Cbr3,
Tmbim6,
Msra,
H2,
Abca1,
Ache,
Chrnb1,
Rasa2,
Adssl1,
Prelp,
Iltifb,
Aox1,
Aqp1,
B2m,
Bcl6,
Serping1,
C1qc,
C4b,
Cacna2d3,
Casp7,
Cd44,
Cd9,
Cfi,
Col4a3,
Cp,
Cr1l,
Crym,
Ctbp2,
Cttn,
Dlg4,
Doc2b,
Edn2,
Emx1,
Enc1,
Ephb3,
Ephx2,
Eri3,
Folr1,
Opn1mw,
Gfap,
Glycam1,
Gna14,
Gnb2,
Pdpn,
Gpm6b,
Ptpn6,
Hdc,
Hsd17b2,
Sdc2,
Mdfic,
Kifc3,
Laptm5,
Gzmm,
Arr3,
Lyz2,
Mab21l1,
Marcks,
Mcl1,
Mcm3,
Mef2c,
Mesp1,
Myo10,
Slc25a15,
Osmr,
Lgals3bp,
Psen2,
Tmsb4x,
Pygm,
Rab3d,
Rps17,
S100a1,
S100a6,
Ccl9,
Exoc4,
Sema3b,
Sez6,
Sh2d1a,
Slc12a4,
Slc16a2,
Slc19a1,
Slc1a1,
Slc6a2,
Dtx4,
Klhl29,
Snx30,
Sdc3,
Mtss1
|
24146773 |
PLoS ONE Hirohito Shimizu , Atsushi Kubo , Kenta Uchibe , Megumi Hashimoto , Shigetoshi Yokoyama , Shuji Takada , Kazuhiko Mitsuoka , Hiroshi Asahara |
2013-01-01 |
Etv5,
Isl2,
Barhl2,
Kank1,
Osr2,
Ankrd1,
Pnrc1,
Nop2,
Lmx1a,
Tshz1,
Alx4,
Nr2f2,
Atf1,
Atoh1,
Bach1,
Barx1,
Prdm1,
Smyd1,
Btg2,
Runx2,
Runx1,
Runx1t1,
Cdk4,
Cdx2,
Cebpa,
Cited1,
Cnbp,
Creb3,
Ctbp2,
Dlx2,
Dlx3,
Dlx4,
Dlx5,
Arid3a,
Ebf1,
Egr1,
Emx2,
En1,
En2,
Eomes,
Epas1,
Evx2,
Eya2,
Srsf10,
Fhl2,
Foxc2,
Fli1,
Gata1,
Gata2,
Gata6,
Gbx2,
Gli1,
Gli2,
Gli3,
Aes,
Gsc,
Hand1,
Hand2,
Hes1,
Hes3,
Hes5,
Hey1,
Foxd1,
Onecut1,
Hnrnpab,
Hoxa10,
Hoxa11,
Hoxa7,
Hoxa9,
Hoxb1,
Hoxb13,
Hoxb5,
Hoxc5,
Hoxc6,
Hoxd10,
Hoxd12,
Hoxd3,
Hoxd4,
Hoxd9,
Hsp90ab1,
Elavl2,
Id3,
Irx1,
Irx2,
Irx3,
Isl1,
Jarid2,
Lef1,
Lhx1,
Lhx2,
Lhx8,
Lmo2,
Lmo4,
Lmx1b,
Mbd2,
Mcm2,
Meis1,
Meox1,
Meox2
|
22988430 |
Front Neurosci Carrie B Wiese , Sara Ireland , Nicole L Fleming , Jing Yu , M Todd Valerius , Kylie Georgas , Han Sheng Chiu , Jane Brennan , Jane Armstrong , Melissa H Little , Andrew P McMahon , E Michelle Southard-Smith |
2012-01-01 | - |
21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
21677750 |
A conditional knockout resource for the genome-wide study of mouse gene function. Nature William C Skarnes , Barry Rosen , Anthony P West , Manousos Koutsourakis , Wendy Bushell , Vivek Iyer , Alejandro O Mujica , Mark Thomas , Jennifer Harrow , Tony Cox , David Jackson , Jessica Severin , Patrick Biggs , Jun Fu , Michael Nefedov , Pieter J de Jong , A Francis Stewart , Allan Bradley |
2011-06-15 | - |
21267068 |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. Graciana Diez-Roux , Sandro Banfi , Marc Sultan , Lars Geffers , Santosh Anand , David Rozado , Alon Magen , Elena Canidio , Massimiliano Pagani , Ivana Peluso , Nathalie Lin-Marq , Muriel Koch , Marchesa Bilio , Immacolata Cantiello , Roberta Verde , Cristian De Masi , Salvatore A Bianchi , Juliette Cicchini , Elodie Perroud , Shprese Mehmeti , Emilie Dagand , Sabine Schrinner , Asja Nürnberger , Katja Schmidt , Katja Metz , Christina Zwingmann , Norbert Brieske , Cindy Springer , Ana Martinez Hernandez , Sarah Herzog , Frauke Grabbe , Cornelia Sieverding , Barbara Fischer , Kathrin Schrader , Maren Brockmeyer , Sarah Dettmer , Christin Helbig , Violaine Alunni , Marie-Annick Battaini , Carole Mura , Charlotte N Henrichsen , Raquel Garcia-Lopez , Diego Echevarria , Eduardo Puelles , Elena Garcia-Calero , Stefan Kruse , Markus Uhr , Christine Kauck , Guangjie Feng , Nestor Milyaev , Chuang Kee Ong , Lalit Kumar , MeiSze Lam , Colin A Semple , Attila Gyenesei , Stefan Mundlos , Uwe Radelof , Hans Lehrach , Paolo Sarmientos , Alexandre Reymond , Duncan R Davidson , Pascal Dollé , Stylianos E Antonarakis , Marie-Laure Yaspo , Salvador Martinez , Richard A Baldock , Gregor Eichele , Andrea Ballabio |
2011-01-18 | - |
排名 | 科研单位 | 文献 |
---|---|---|
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