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30718 notch1a

30718

notch1a

notch receptor 1a

protein-coding

Danio rerio

基因描述

Type Description
Definition notch receptor 1a

研究结论

Date Results Publications
2021-02-27 13:51:00 Haematopoietic stem cell-dependent Notch transcription is mediated by p53 through the Histone chaperone Supt16h. 33230303
2020-09-05 13:57:00 Notch-Mediated Determination of Hair-Bundle Polarity in Mechanosensory Hair Cells of the Zebrafish Lateral Line. 31668618
2019-12-28 11:49:00 To clarify the role of Notch signaling in osteogenesis, we established a zebrafish model, in which Notch1a intracellular domain (N1aICD) was specifically expressed in the osteoblasts. We found that overexpression of N1aICD in osteoblasts caused hyperosteogeny in the column region of zebrafish with the morphology of narrowed neural/hemal canals 31344827
2019-11-23 10:47:00 Notch1a plays roles in inhibiting many immunity-related genes and could comprehensively mediate the innate immune response by regulating TLRs, nucleotide-binding-oligomerization-domain-like receptors (NLRs), lectins, complement, ILs, chemokines, TNF, cathepsin, and serpin. 31271837
2019-02-23 12:47:00 Data show that in endothelial cells, bone morphogenetic protein endothelial precursor-derived regulator (BMPER) and twisted gastrulation protein homolog 1 (TWSG1) are necessary for regular Notch signaling activity. 29473997

名称对应

Type IDs
Synonymous des, n1a, wu:fc01e02, wu:fc37a05
Gene
UniProtKB-ID: NOTC1_DANRE
UniprotKB: P46530
UniParc: UPI000013056E
EMBL: X69088
KO: dre:30718
Nucleutide sequences
EMBL-CDS: CAA48831.1
Protein sequencees
RefSeq: NP_571516.1
Others
UniRef100: UniRef100_P46530
UniRef90: UniRef90_P46530
UniRef50: UniRef50_P46530
UniGene: Dr.75753, Dr.137595

全选

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研究热度

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