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30705 fgfr1a

30705

fgfr1a

fibroblast growth factor receptor 1a

protein-coding

Danio rerio

基因描述

Type Description
Definition fibroblast growth factor receptor 1a

研究结论

Date Results Publications
2020-08-01 13:20:00 As the AB fish, fgfr1a mutant fish losing dyadic interactions showed a typical loser effect and social subordination resulted in an activation of the brain serotonergic system in fgfr1a mutants as well as in AB fish. Overall the effects of dyadic interaction were similar in fgfr1a mutant fish and zebrafish of the AB strain. 31085203
2020-01-04 10:48:00 Knockdown of znfl1s led to abnormal cilia formation by the downregulation of fgfr1a and foxj1a expression. 30317609
2017-07-29 11:25:00 Here we demonstrate that of the nine FGFR1 mutations recently detected in our screen of over 200 HPE probands by next generation sequencing, only five distinct mutations in the kinase domain behave as dominant-negative mutations in zebrafish over-expression assays 26931467
2014-12-20 13:22:00 we show that minimal amounts of Fgfr1a or Fgfr2 are required to initiate a regulatory cascade in pharyngeal endoderm reducing expression of fsta, thereby allowing correct BMP signaling to the maturing chondrocytes of the head cartilage. 24176552
2013-09-14 10:48:00 Considering all these findings, we concluded that as in mammals, in adult zebrafish the metabolism of lipid and bile acids in the liver are regulated by Fgf signaling. 22820869

名称对应

Type IDs
Synonymous FGFR-1-A, bFGF-R-1-A, cb231, fgfr1, sb:cb231
Gene
UniProtKB-ID: FGR1A_DANRE
UniprotKB: Q90Z00
UniParc: UPI0000EB6F1B, UPI0001A6153B, UPI0000EB6F20, UPI0001A6153C, UPI0001567386
EMBL: AY197501, CR376860, AF389400, AY197500, BX247873, CU458752, AY197498, BC162342, AY197499
Ensembl: ENSDARG00000011027
KO: dre:30705
Nucleutide sequences
EMBL-CDS: AAO45658.1, AAK64494.1, CAP19404.1, AAO45660.1, CAM13574.1, CAM60064.1, CAK04365.2, CAP19403.1, AAI62342.1, AAO45661.1, CAM13573.2, CAP19402.1, AAO45659.1
Gene_ORFName: si:ch211-198o12.1
Ensembl_TRS: ENSDART00000167394, ENSDART00000147742, ENSDART00000135166, ENSDART00000024882
Protein sequencees
Ensembl_PRO: ENSDARP00000013742, ENSDARP00000115638, ENSDARP00000116533, ENSDARP00000131679
RefSeq: NP_001296328.1, NP_694494.2, NP_001296329.1, XP_009302578.1, XP_009302579.1
Others
UniRef100: UniRef100_Q90Z00
UniRef90: UniRef90_Q90Z00
UniRef50: UniRef50_P11362
UniGene: Dr.78806, Dr.83393

全选

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研究热度

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