| Type | Description |
|---|---|
| Definition | hypocretin neuropeptide precursor |
| Date | Results | Publications |
|---|---|---|
| 2020-10-24 13:54:00 | Reduced Plasma Orexin-A Concentrations are Associated with Cognitive Deficits in Anorexia Nervosa. | 31133733 |
| 2020-08-22 15:25:00 | Orexin-A protects against oxygen-glucose deprivation/reoxygenation-induced cell damage by inhibiting endoplasmic reticulum stress-mediated apoptosis via the Gi and PI3K signaling pathways. | 31233841 |
| 2020-08-15 19:05:00 | Circulating orexin changes during withdrawal are associated with nicotine craving and risk for smoking relapse. | 30117237 |
| 2020-03-28 10:06:00 | Orexin A ameliorates high glucose-induced oxidative stress and activation of the NLRP3 inflammasome. It exerts potent antioxidant effects in human aortic endothelial cells exposed to high glucose by inhibiting mitochondrial reactive oxygen species and expression of NOX4, TxNIP, and HMGB1. | 31351069 |
| 2019-08-03 10:37:00 | Silence of OX1R completely abolished the inhibitory function of orexin in attachment of THP-1 cells. Collectively, our data suggest that orexin A ameliorated endothelial dysfunction under inflammatory stimuli. | 30207631 |
| Type | IDs |
|---|---|
| Synonymous | NRCLP1, OX, PPOX |
| Gene |
UniProtKB-ID:
OREX_HUMAN
UniprotKB:
O43612
UniParc:
UPI0000130E6F
EMBL:
AF041240,
AF118885
Ensembl:
ENSG00000161610
KO:
hsa:3060
|
| Nucleutide sequences |
EMBL-CDS:
AAD24459.1,
AAC39600.1
Ensembl_TRS:
ENST00000293330
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000293330
RefSeq:
NP_001515.1
|
| Others |
UniRef100:
UniRef100_O43612
UniRef90:
UniRef90_O43612
UniRef50:
UniRef50_O43612
UniGene:
Hs.158348
CCDS:
CCDS11421.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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