| Type | Description |
|---|---|
| Definition | MyoD family inhibitor domain containing |
| Date | Results | Publications |
|---|---|---|
| 2020-12-05 13:00:00 | Opposite Roles of the JMJD1A Interaction Partners MDFI and MDFIC in Colorectal Cancer. | 32457453 |
| 2017-06-03 11:38:00 | GR directly represses the MDFIC gene, revealing a negative feedback loop by which glucocorticoids limit MDFIC activity. These findings identify a new binding partner for cytoplasmic GR that modulates the receptor transcriptome and contributes to the tissue-specific actions of glucocorticoids. | 28223352 |
| 2016-06-11 11:58:00 | HIC specifically interacts with HTLV-1 Tax and negatively regulates Tax transactivational activity by altering its subcellular distribution and stability. | 26469549 |
| 2011-07-02 11:23:00 | We demonstrate that HIC selectively interferes with Rev NLS interaction with importin beta and impedes its nuclear import and function, but does not affect Rev nuclear import mediated by transportin. | 21401918 |
| 2010-07-12 11:45:00 | These data reveal for the first time that I-mfa domain proteins interact with LANA and negatively regulate LANA-mediated activation of Wnt signaling-dependent transcription by inhibiting the formation of the LANA.GSK-3beta complex. | 20417616 |
| Type | IDs |
|---|---|
| Synonymous | HIC, MDFIC1 |
| Gene |
UniProtKB-ID:
MDFIC_HUMAN
UniprotKB:
Q9P1T7
UniParc:
UPI000006E384,
UPI0000072373
EMBL:
AY196485,
AF054589
Ensembl:
ENSG00000135272
KO:
hsa:29969
|
| Nucleutide sequences |
EMBL-CDS:
AAP33842.1,
AAF36999.1,
AAF36998.1
Ensembl_TRS:
ENST00000393486
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000377126
RefSeq:
NP_951038.1,
NP_001159818.3,
NP_001159817.1
|
| Others |
UniRef100:
UniRef100_Q9P1T7
UniRef90:
UniRef90_Q9P1T7
UniRef50:
UniRef50_Q9P1T7
UniGene:
Hs.741413
CCDS:
CCDS55155.1,
CCDS34737.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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