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2993 GYPA

2993

GYPA

glycophorin A (MNS blood group)

protein-coding

Homo sapiens

基因描述

Type Description
Definition glycophorin A (MNS blood group)

研究结论

Date Results Publications
2021-03-20 13:27:00 Novel hybrid genes and a splice site mutation encoding the St(a) antigen among Japanese blood donors. 32394466
2021-02-06 13:55:00 Structural variation of the malaria-associated human glycophorin A-B-E region. 32600246
2020-12-05 13:03:00 Characterization of GYP*Mur and novel GYP*Bun-like hybrids in Thai blood donors reveals a qualitatively altered s antigen. 32201961
2019-03-30 10:31:00 These results are consistent with malaria acting as a selective pressure on GYPA, but also suggest that another selective force has resulted in a similar pattern of variation in Europeans. Accordingly, GYPA has perhaps a more complex evolutionary history, wherein on a global scale, spatially varying selective pressures have governed its natural history. 29362874
2018-06-16 11:21:00 Cell viability and surface expression of transferrin receptor (CD71) and glycophorin A (GPA) were analyzed before and after re-culture by flow cytometry. These studies show differential sensitivities of these surface proteins on K562 cells to proteases, and suggest molecular mechanisms of transmembrane protein transport and cycling. 28980921

名称对应

Type IDs
Synonymous CD235a, GPA, GPErik, GPSAT, HGpMiV, HGpMiXI, HGpSta(C), MN, MNS, PAS-2
Gene
UniProtKB-ID: GLPA_HUMAN, A0A2R8Y7F9_HUMAN, E9PD10_HUMAN, A0A0C4DFT7_HUMAN, Q14419_HUMAN
UniprotKB: P02724, A0A2R8Y7F9, E9PD10, A0A0C4DFT7, Q14419
UniParc: UPI000387CE43, UPI000016A9B9, UPI0001B3055D, UPI00000705EE, UPI0001D3B937, UPI00018995F6, UPI000020B503
EMBL: GU347002, M24134, GU347003, AC107223, L31860, M24126, M12857, BC013328, EU338233, EU338231, M24124, EU338234, BC005319, M24127, AK290561, M24123, X51798, X57023, M36281, X08054, M24128
Ensembl: ENSG00000170180
KO: hsa:2993
Nucleutide sequences
EMBL-CDS: ADU25341.1, CAA30843.1, AAA52768.1, AAA88044.1, AAA52624.1, ACA96792.1, AAH13328.1, CAA36095.1, AAA88051.1, ADU25340.1, ACA96789.1, AAH05319.1, ACA96791.1, BAF83250.1, CAA40340.1
Ensembl_TRS: ENST00000646447, ENST00000324022, ENST00000642713, ENST00000642295, ENST00000512064, ENST00000360771, ENST00000641688
Protein sequencees
Ensembl_PRO: ENSP00000324483, ENSP00000494092, ENSP00000495922, ENSP00000496079, ENSP00000426130, ENSP00000493142, ENSP00000354003
RefSeq: NP_001295119.1, NP_001295116.1, XP_016863624.1, XP_016863625.1, XP_016863623.1, NP_002090.4
Others
UniRef100: UniRef100_Q14419, UniRef100_A0A2R8Y7F9, UniRef100_E9PD10, UniRef100_A0A0C4DFT7, UniRef100_P02724
UniRef90: UniRef90_A0A2R8Y7F9, UniRef90_P02724, UniRef90_E9PD10
UniRef50: UniRef50_P02724, UniRef50_P02724-3
UniGene: Hs.434973
CCDS: CCDS34069.1, CCDS82959.1

全选

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