| Type | Description |
|---|---|
| Definition | phosphatidylinositol transfer protein, alpha |
| Date | Results | Publications |
|---|---|---|
| 2017-09-30 13:56:00 | Data suggest that (1) interaction of Pitpna with membrane/lipid bilayer is spontaneous and mediated by four specific protein substructures; (2) ability of Pitpna to initiate closure around PC ligand is accompanied by loss of flexibility of two helix/loop regions, as well as of C-terminal helix; (3) energy barrier of PC/PI extraction from membrane is lowered by hydrogen bonding between lipid and Pitpna. | 28718450 |
| 2010-01-21 00:00:00 | Lower protein expression of PI-TP(alpha and beta) in aged brain and in PD. | 16779671 |
| 2001-10-23 14:59:00 | Cys-to-Ala mutations of PITP show that neither Cys95 nor Cys188 is essential for lipid transfer activity; however, chemical modification of Cys95 results in the loss of lipid transfer activity. | 11478882 |
| Type | IDs |
|---|---|
| Synonymous | Pitpn |
| Gene |
UniProtKB-ID:
PIPNA_RAT
UniprotKB:
P16446
UniParc:
UPI000011DD51
EMBL:
M25758,
BC070945
Ensembl:
ENSRNOG00000003846
KO:
rno:29525
|
| Nucleutide sequences |
EMBL-CDS:
AAH70945.1,
AAA41984.1
Ensembl_TRS:
ENSRNOT00000090554
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000072145
RefSeq:
NP_058927.1
|
| Others |
UniRef100:
UniRef100_P16446
UniRef90:
UniRef90_Q00169
UniRef50:
UniRef50_Q00169
UniGene:
Rn.9771
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 28718450 |
J Biol Chem Aby Grabon , Adam OrÅowski , Ashutosh Tripathi , Joni Vuorio , Matti Javanainen , Tomasz Róg , Max Lönnfors , Mark I McDermott , Garland Siebert , Pentti Somerharju , Ilpo Vattulainen , Vytas A Bankaitis |
2017-09-01 | - |
| 23376485 |
Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. J Proteomics Marco Prunotto , Annarita Farina , Lydie Lane , Agnès Pernin , Jürg Schifferli , Denis F Hochstrasser , Pierre Lescuyer , Solange Moll |
2013-04-26 |
CDH2,
GNPDA1,
C1orf68,
PDCD6IP,
PDCD6,
TOM1L1,
CDH6,
IL18BP,
DPP3,
SNUPN,
ARPC5,
CDH11,
ARPC4,
ARPC3,
ARPC1B,
ACTR3,
ACTR2,
TSPAN1,
ARPC2,
ACTR1B,
ACTR1A,
CDH13,
PDIA6,
TRAP1,
PDZK1IP1,
ATP6AP2,
DHRS2,
NUTF2,
FLOT1,
PSMD14,
RIDA,
GLYAT,
ZMPSTE24,
STUB1,
RTN3,
LANCL1,
CRISP3,
SIRPB1,
AKR1A1,
TFG,
TUBA1B,
BPNT1,
TUBB4B,
BTN2A2,
NDRG1,
RACK1,
ST3GAL6,
CPQ,
WFDC2,
BASP1,
IFITM3,
CDSN,
LYPLA1,
FAM3C,
ACAA2,
VAV3,
TOMM40,
BAIAP2,
ATP5H,
CEACAM5,
CAP1,
VAT1,
FBLN5,
CIB1,
GLRX3,
PROCR,
ARL6IP5,
ARPC1A,
OLFM4,
CEL,
CCT7,
CCT4,
CCT2,
NPC2,
DNPH1,
PAICS,
MYL12A,
ATP5L,
YKT6,
PMVK,
GNA13,
B3GNT2,
CCT8,
CETP,
CFL1,
PTGES3,
RBBP9,
MASP2,
CTSC,
GIPC1,
AHCYL1,
IQGAP2,
VAMP5,
CFTR,
ALDH1L1,
FTCD,
RUVBL2,
PGRMC1,
FGL2
|
| 22822086 |
J Biol Chem Kathryn Garner , Alan N Hunt , Grielof Koster , Pentti Somerharju , Emily Groves , Michelle Li , Padinjat Raghu , Roman Holic , Shamshad Cockcroft |
2012-09-14 | - |
| 22871113 |
Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. J. Proteome Res. Chan Hyun Na , Drew R Jones , Yanling Yang , Xusheng Wang , Yanji Xu , Junmin Peng |
2012-09-07 |
Rab1b,
Tmem59,
Msh6,
LOC100360426,
Sncb,
Csnk1a1,
Magi2,
Cxcl2,
Dnm1l,
Gng3,
Hcn2,
Clasp2,
Ubqln1,
Gne,
Stx1a,
Txn1,
Sec14l2,
Gripap1,
Mprip,
Slc6a9,
Ralb,
Ap2m1,
Nrxn2,
Slc17a7,
Vcp,
Cap2,
Dlgap2,
Lmnb1,
Trim28,
Epb41l3,
Ube2n,
Gp1bb,
Nup155,
Bin1,
Rpl6,
H3f3b,
Nlgn2,
Prdx1,
Psmc4,
Psmc1,
Epn1,
Ppp2r1a,
Hnrnpk,
Lrrc7,
Txnip,
Uba3,
Sv2b,
Tpm3,
Sv2a,
Atp6v1b2,
Rps20,
Slc8a2,
Rps3,
Faf1,
Ap2b1,
Dnm1,
Cacng8,
Cdk5,
Txnl1,
Ggt7,
Prkcd,
Palm,
Atp2c1,
Dynlrb1,
Kcnh7,
Xpnpep1,
Atxn10,
Kcnq2,
Cry2,
Rab3c,
Ndrg2,
Camk2g,
Pabpc1,
Eef1a1,
Slc12a5,
Acsbg1,
Tmem176b,
Nme1,
Tecr,
Syngap1,
Hip1,
Gpm6b,
Ehd4,
Rasgrf1,
Plpp3,
Stip1,
Caly,
Aldoa,
Aldoc,
Atp1a1,
Atp1a2,
Atp1a3,
Atp2b2,
Cacna1c,
Calm1,
Camk2d,
Ckb,
Eno1,
Gapdh
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 18636990 |
Dynamics of lipid transfer by phosphatidylinositol transfer proteins in cells. Traffic Sadaf Shadan , Roman Holic , Nicolas Carvou , Patrick Ee , Michelle Li , Judith Murray-Rust , Shamshad Cockcroft |
2008-09-01 | - |
| 18570454 |
J. Proteome Res. Dukjin Kang , Sunok Oh , Sung-Min Ahn , Bong-Hee Lee , Myeong Hee Moon |
2008-08-01 |
TAF6L,
MTMR11,
AGAP2,
GLIPR2,
CYP2J2,
DDX11,
DHX36,
BPTF,
RHOBTB3,
SYNE2,
ARHGEF18,
DAAM2,
TAB3,
GALNT3,
APPL1,
PCLO,
GLRX,
GOLGA4,
TNPO1,
LAD1,
MARK3,
ATP2B2,
NUMA1,
ANKFY1,
PEX1,
PITPNA,
UBASH3A,
EXOSC9,
AUP1,
TEX14,
PTGS1,
RBSN,
SRSF7,
HIRA,
TXNRD1,
LUZP1,
ABHD8,
PIP4K2C,
NCOA3,
PLVAP,
CARD11,
CTSF,
NAPG,
CDKL1,
TAX1BP1,
MTMR2,
RASSF9,
MAPKAPK2,
SYAP1,
IQCB1,
SAFB2,
GREB1,
RIMS2,
TOMM70,
THRAP3
|
| 17634366 |
Proteolipid protein is required for transport of sirtuin 2 into CNS myelin. J. Neurosci. Hauke B Werner , Katja Kuhlmann , Siming Shen , Marina Uecker , Anke Schardt , Kalina Dimova , Foteini Orfaniotou , Ajit Dhaunchak , Bastian G Brinkmann , Wiebke Möbius , Lenny Guarente , Patrizia Casaccia-Bonnefil , Olaf Jahn , Klaus-Armin Nave |
2007-07-18 |
Napg,
Napa,
Rap1a,
Aco2,
Actb,
Actg1,
Alb,
Slc25a4,
Slc25a5,
Prdx3,
Arf6,
Ass1,
Atp1a1,
Atp1b1,
Atp5a1,
Atp5b,
Atp5c1,
Atp5f1,
Atp6v1a,
Atp6v1b2,
Canx,
Car2,
Cct2,
Cct3,
Cct5,
Cdc42,
Ckb,
Ckmt1,
Cnp,
Cntn1,
Cox5a,
Cox6a1,
Dpysl2,
Cryab,
Cycs,
Dld,
Dnm1,
Eef1a1,
Eef1a2,
Ehd1,
Eno2,
Igsf8,
Fscn1,
Gdi1,
Gdi2,
Gfap,
Glul,
Gnao1,
Gnb1,
Gnb2,
Gnb4,
Gnb5,
Got2,
Gpi1,
Pdia3,
Hspa5,
Gstm1,
Hspa8,
Hspd1,
Hspa2,
Hsp90aa1,
Hspa9,
Ldhb,
Mag,
Mbp,
Mif,
Mobp,
Mog,
Mdh2,
Mdh1,
Msn,
Napb,
Ncam1,
Ndrg1,
Sept2,
Nefl,
Nefm,
Nme1,
Nme2,
Nsf,
Cldn11,
Prdx1,
Pdcd6ip,
Pdha1,
Pgam1,
Phb,
Slc25a3,
Pitpna,
Pkm,
Plcb1,
Plp1,
Sept4,
Rdx,
Sept8,
Snap25,
Sod1,
Sod2,
Sptan1,
Stip1
|
| 16779671 |
Phosphatidylinositol transfer protein expression altered by aging and Parkinson disease. Cell. Mol. Neurobiol. MaÅgorzata Chalimoniuk , Gerry T Snoek , Agata Adamczyk , Andrzej MaÅecki , Joanna B Strosznajder |
2006-06-16 | - |
| 16274224 |
Biochemistry Paul B Vordtriede , Chuong N Doan , Jacqueline M Tremblay , George M Helmkamp , Marilyn D Yoder |
2005-11-15 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
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| 排名 | 研究人员 | 文献 |
|---|---|---|
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