| Type | Description |
|---|---|
| Definition | fumarylacetoacetate hydrolase |
| Date | Results | Publications |
|---|---|---|
| 2018-06-02 11:10:00 | Using CRISPR/Cas9 technique, Fah(-/-) rats were generated. They faithfully represented major phenotypic and biochemical manifestations of human ereditary tyrosinemia type I (HT1), including hypertyrosinemia, liver failure, and renal tubular damage. More importantly, they developed remarkable liver fibrosis and cirrhosis which can be prevented with wild-type hepatocytes transplantation. | 27510266 |
| 2015-05-16 10:40:00 | Urinary excretion of fumarylacetoacetase is a potential biomarker candidate of predisposition to kidney injury induced by sub-toxic administration of cisplatin. | 25677510 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
FAAA_RAT
UniprotKB:
P25093
UniParc:
UPI000012A423
EMBL:
BC076381,
M77694
KO:
rno:29383
|
| Nucleutide sequences |
EMBL-CDS:
AAA41142.1,
AAH76381.1
|
| Protein sequencees |
RefSeq:
NP_058877.1
|
| Others |
UniRef100:
UniRef100_P25093
UniRef90:
UniRef90_P25093
UniRef50:
UniRef50_P16930
UniGene:
Rn.9195
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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