| Type | Description |
|---|---|
| Definition | glutathione peroxidase 4 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-22 15:25:00 | Quantitative proteomic analyses reveal that GPX4 downregulation during myocardial infarction contributes to ferroptosis in cardiomyocytes. | 31685805 |
| 2019-11-09 10:58:00 | Genetic-overexpression of GPX4 effectively increased level of GPX4 in the brain, and clearly relieved neuronal dysfunction, brain edema, blood brain barrier (BBB) injury, oxidative stress and inflammation after ICH. | 30205109 |
| 2018-05-26 10:25:00 | Gpx4-catalyzed reduction of lipid hydroperoxides in lipid membranes has been described. | 28709976 |
| 2016-08-06 10:21:00 | MS/MS analysis of oxidized rat GPx4 complies with the predicted structure, an 8-membered ring, in which selenium is bound as selenenylamide to the protein backbone. | 26163004 |
| 2016-03-12 11:11:00 | mitochondria-targeted antioxidant SkQ1 (50 nmol/kg during 5 days) significantly increased the mRNA levels of Nrf2 transcription factor and Nrf2-induced genes encoding antioxidant enzymes SOD1, SOD2, CAT, and GPx4 in rat peripheral blood leukocytes. | 26071777 |
| Type | IDs |
|---|---|
| Synonymous | Gshpx-4, Phgpx, gpx-4, snGpx |
| Gene |
UniProtKB-ID:
GPX4_RAT
UniprotKB:
P36970
UniParc:
UPI000164287A,
UPI0000503CC7,
UPI0000503CC8
EMBL:
X82679,
AF274028,
AJ537598,
AY570513,
AB072798,
U37427,
L24896
Ensembl:
ENSRNOG00000013604
KO:
rno:29328
|
| Nucleutide sequences |
EMBL-CDS:
AAK74113.1,
CAD61277.1,
AAC52503.2,
CAD61278.1,
AAS76675.1,
CAD61276.1,
BAC87836.1,
AAA41842.2,
CAA57996.1
Ensembl_TRS:
ENSRNOT00000093426,
ENSRNOT00000093376
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000076198,
ENSRNOP00000076309
RefSeq:
NP_001354972.1,
NP_001034938.1,
NP_058861.3
|
| Others |
UniRef100:
UniRef100_P36970
UniRef90:
UniRef90_O70325
UniRef50:
UniRef50_O70325
UniGene:
Rn.3647
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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