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2926 GRSF1

2926

GRSF1

G-rich RNA sequence binding factor 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition G-rich RNA sequence binding factor 1

研究结论

Date Results Publications
2021-01-09 13:30:00 Identification of the COMM-domain containing protein 1 as specific binding partner for the guanine-rich RNA sequence binding factor 1. 32645484
2020-10-31 13:12:00 GRSF1 is an age-related regulator of senescence. 30944385
2020-09-12 16:01:00 A novel miRNA identified in GRSF1 complex drives the metastasis via the PIK3R3/AKT/NF-kappaB and TIMP3/MMP9 pathways in cervical cancer cells. 31474757
2019-10-19 12:31:00 our results indicate that GRSF1 helps preserve mitochondrial homeostasis, in turn preventing oxidative DNA damage and the activation of mTOR and NF-kappaB, and suppressing a transcriptional pro-inflammatory program leading to increased IL6 production. 30753671
2019-10-12 12:40:00 These findings suggest that Twinkle is essential for RNA organization in granules, and that mtSSB is involved in the recently proposed GRSF1-mtRNA degradosome pathway, a route suggested to be particularly aimed at degradation of G-quadruplex prone long non-coding mtRNAs. 30715486

名称对应

Type IDs
Gene
UniProtKB-ID: GRSF1_HUMAN, A0A024RD99_HUMAN
UniprotKB: Q12849, A0A024RD99
UniParc: UPI0000EE2D66, UPI0001838834
EMBL: AK094806, U07231, AK127161, AK097055, CH471057, AC021989, AK090755, AK056891, AK095799, BC040485
Ensembl: ENSG00000132463
KO: hsa:2926
Nucleutide sequences
EMBL-CDS: BAC03513.1, AAY40942.1, EAX05634.1, BAG53131.1, AAC95399.1, BAC86863.1, BAG52934.1, EAX05631.1, BAG53414.1, AAH40485.1, BAG51822.1, EAX05633.1, EAX05632.1
Gene_ORFName: hCG_17000
Ensembl_TRS: ENST00000502323, ENST00000254799
Protein sequencees
Ensembl_PRO: ENSP00000254799, ENSP00000425430
RefSeq: NP_001091947.1, XP_011530199.1, NP_002083.4
Others
UniRef100: UniRef100_Q12849, UniRef100_A0A024RD99
UniRef90: UniRef90_H2QPM2, UniRef90_Q12849
UniRef50: UniRef50_Q12849
UniGene: Hs.309763
CCDS: CCDS47069.1, CCDS47070.1

全选

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