| Type | Description |
|---|---|
| Definition | izumo sperm-egg fusion 1 |
| Date | Results | Publications |
|---|---|---|
| 2016-07-30 11:19:00 | crystal structures of human IZUMO1 and JUNO in unbound and bound conformations | 27309818 |
| 2016-07-30 11:19:00 | crystal structures of human IZUMO1, JUNO and the IZUMO1-JUNO complex, establishing the structural basis for the IZUMO1-JUNO-mediated sperm-oocyte interaction | 27309808 |
| 2013-07-20 10:43:00 | these findings indicate that human sperm expresses Izumo protein, and the immunoinfertile female sera have circulating isoantibodies against this protein. | 23279005 |
| 2010-01-21 00:00:00 | We observed in our populations two combinations of four polymorphisms that appeared to be preferentially linked (CGG-CG and TAA-TT) without any significant difference between different genotype repartitions. | 18082733 |
| 2010-01-21 00:00:00 | human sperm contain Izumo and addition of the antibody against human Izumo left the sperm unable to fuse with zona-free hamster eggs [Izumo] | 15759005 |
| Type | IDs |
|---|---|
| Synonymous | IZUMO, OBF |
| Gene |
UniProtKB-ID:
IZUM1_HUMAN
UniprotKB:
Q8IYV9
UniParc:
UPI000034E4AC,
UPI00006688B9,
UPI00001609C7
EMBL:
BC034769,
AC009002,
AY552609,
AY552610,
AB195682
Ensembl:
ENSG00000182264
KO:
hsa:284359
|
| Nucleutide sequences |
EMBL-CDS:
BAD91012.1,
AAS59146.1,
AAS59145.1,
AAH34769.1
Ensembl_TRS:
ENST00000595937,
ENST00000595517,
ENST00000332955
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000470144,
ENSP00000327786,
ENSP00000471815
RefSeq:
NP_872381.2,
NP_001308793.1,
NP_001308794.1
|
| Others |
UniRef100:
UniRef100_Q8IYV9
UniRef90:
UniRef90_Q8IYV9
UniRef50:
UniRef50_Q8IYV9
UniGene:
Hs.400688
CCDS:
CCDS12732.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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