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Preliminary study on the role of the human IZUMO gene in oocyte-spermatozoa fusion failure.

Fertil. Steril.2008 Oct;90(4):1246-8. Epub 2007 Dec 20
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摘要


We studied the IZUMO gene 9 coding exons sequence in four groups of patients including those with fertilization failure by conventional IVF. We observed in our populations two combinations of four polymorphisms that appeared to be preferentially linked (CGG-CG and TAA-TT) without any significant difference between different genotype repartitions.

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