| Type | Description |
|---|---|
| Definition | translocase of outer mitochondrial membrane 70A |
| Date | Results | Publications |
|---|---|---|
| 2019-07-06 12:00:00 | TOM70, but not TOM20, clusters in distinct OMM foci, frequently overlapping with sites in which the endoplasmic reticulum (ER) contacts mitochondria. Functionally, TOM70 depletion specifically impairs inositol trisphosphates (IP3)-linked ER to mitochondria Ca(2+) transfer. This phenomenon is dependent on the capacity of TOM70 to interact with IP3-receptors and favor their functional recruitment close to mitochondria. | 29395920 |
| 2018-05-19 10:28:00 | Genetic manipulation revealed that loss of Tom70 decreased mitochondrial MICU1 localization and aggravated myocardial ischemia/reperfusion injury; whereas, overexpression of Tom70 protected myocardial ischemia/reperfusion injury, which was eliminated by MICU1 ablation. | 28703803 |
| 2017-04-22 12:44:00 | Our findings showed that Tom70 is essential for melatonin-induced protection against post-myocardial infarction injury | 27706848 |
| 2013-12-07 11:54:00 | PINK1 is imported into mitochondria by a unique pathway that is independent of the TOM core complex but crucially depends on the import receptor Tom70 | 23472196 |
| 2010-01-21 00:00:00 | S100A2 and S100A6 interact with another TPR protein Tom70 and regulate the Tom70-ligand interaction in vitro | 18669640 |
| Type | IDs |
|---|---|
| Synonymous | 2610044B22Rik, D16Ium22, D16Ium22e, D16Wsu109e, Tom70, Tomm70, mKIAA0719 |
| Gene |
UniProtKB-ID:
TOM70_MOUSE
UniprotKB:
Q9CZW5
UniParc:
UPI00000EB1D3
EMBL:
BC139420,
AK012084,
AK083586,
BC057096,
AK150429,
BC139421,
AK145458
Ensembl:
ENSMUSG00000022752
KO:
mmu:28185
|
| Nucleutide sequences |
EMBL-CDS:
BAE26448.1,
AAI39421.1,
AAI39422.1,
BAC38960.1,
BAE29552.1,
AAH57096.1,
BAB28018.1
Ensembl_TRS:
ENSMUST00000166897
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000129186
RefSeq:
NP_613065.2
|
| Others |
UniRef100:
UniRef100_Q9CZW5
UniRef90:
UniRef90_O94826
UniRef50:
UniRef50_O94826
UniGene:
Mm.213292
CCDS:
CCDS28227.1
|