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27973 Vkorc1

27973

Vkorc1

vitamin K epoxide reductase complex, subunit 1

protein-coding

Mus musculus

基因描述

Type Description
Definition vitamin K epoxide reductase complex, subunit 1

研究结论

Date Results Publications
2020-12-26 13:12:00 A VKORC1-based SNP survey of anticoagulant rodenticide resistance in the house mouse, Norway rat and roof rat in the USA. 32687688
2019-09-28 11:34:00 The presence of two of the most commonly found amino acid substitutions Leu128Ser and Tyr139Cys associated with house mouse resistance to anticoagulant rodenticides was confirmed. The occurrence of two such mutations is indicative of the occurrence of resistance to anticoagulant rodenticides in house mice in the Eastern region of the island of Ireland. 29540746
2016-04-23 10:04:00 quantified mRNA levels for VKORC1, VKORC1L1, GGCX, and NQO1 and measured VKOR enzymatic activities in 29 different tissues 25747820
2015-05-30 10:07:00 OCN is gamma-carboxylated by the gamma-carboxylase (GGCX) on three glutamic acid residues, a cellular process requiring reduction of vitamin K by a second enzyme, VKORC1. 25753038
2013-12-07 11:27:00 The involvement of VKORC1L1 in VKOR activity partly explains the low susceptibility of some extrahepatic tissues to vitamin K antagonists. 23928358

名称对应

Type IDs
Synonymous D7Wsu86e
Gene
UniProtKB-ID: VKOR1_MOUSE
UniprotKB: Q9CRC0
UniParc: UPI00000235E8
EMBL: AK002742, AK013996, AK008509, AK003237, AK008578, BC031732
Ensembl: ENSMUSG00000096145
KO: mmu:27973
Nucleutide sequences
EMBL-CDS: BAB25708.1, BAB25757.1, BAB22661.1, BAB29106.1, BAB22320.1, AAH31732.1
Ensembl_TRS: ENSMUST00000033074
Protein sequencees
Ensembl_PRO: ENSMUSP00000033074
RefSeq: XP_030098508.1, NP_848715.1
Others
UniRef100: UniRef100_Q9CRC0
UniRef90: UniRef90_Q6TEK4
UniRef50: UniRef50_Q6TEK4
UniGene: Mm.29703
CCDS: CCDS21883.1

全选

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