| Type | Description |
|---|---|
| Definition | ATP-binding cassette, sub-family A (ABC1), member 3 |
| Date | Results | Publications |
|---|---|---|
| 2017-03-11 10:49:00 | mAbca3-rNeo mice demonstrated allele-dependent susceptibility to bleomycin including enhanced weight loss, augmented airspace destruction, and increased fibrosis | 28034695 |
| 2014-05-24 10:45:00 | Abca3 haploinsufficiency results in an altered biochemical and lung mechanical phenotype, as well as a greater lung injury induced by hyperoxia or mechanical ventilation. | 23881110 |
| 2011-07-30 10:23:00 | The majority of mice in which Abca3 was deleted in alveolar type II cells died shortly after birth from respiratory distress related to surfactant deficiency. | 20190032 |
| 2010-01-21 00:00:00 | Plays an essential role in pulmonary surfactant lipid metabolism and lamellar body biogenesis, probably by transporting these lipids as substrates. | 17267394 |
| 2010-01-21 00:00:00 | The phenotype of respiratory failure immediately after birth corresponds to the clinical course of severe ABCA3 mutations in human newborns. | 17577581 |
| Type | IDs |
|---|---|
| Synonymous | 1810036E22Rik, ABC-C, Abc3 |
| Gene |
UniProtKB-ID:
ABCA3_MOUSE,
Q6AXE3_MOUSE,
Q3TN91_MOUSE
UniprotKB:
Q8R420,
Q6AXE3,
Q3TN91
UniParc:
UPI000040284B,
UPI00005B2151,
UPI000024E210
EMBL:
AY083616,
AC154237,
BC079617,
AK165458,
AK154698,
AC117577
Ensembl:
ENSMUSG00000024130
KO:
mmu:27410
|
| Nucleutide sequences |
EMBL-CDS:
BAE32771.1,
AAL99380.1,
AAH79617.1,
BAE38198.1
Ensembl_TRS:
ENSMUST00000079594,
ENSMUST00000039013,
ENSMUST00000117337
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000045285,
ENSMUSP00000078544,
ENSMUSP00000113538
RefSeq:
XP_006524433.1,
NP_001034670.1,
NP_038883.2
|
| Others |
UniRef100:
UniRef100_Q8R420,
UniRef100_Q6AXE3
UniRef90:
UniRef90_Q8R420,
UniRef90_Q6AXE3
UniRef50:
UniRef50_Q8R420,
UniRef50_Q99758
UniGene:
Mm.239470
CCDS:
CCDS37486.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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