| Type | Description |
|---|---|
| Definition | proprotein convertase subtilisin/kexin type 1 inhibitor |
| Date | Results | Publications |
|---|---|---|
| 2018-02-03 11:11:00 | neuronal proSAAS plays an important role in proteostatic processes. | 27457957 |
| 2014-01-25 11:26:00 | Results show significant differences in distribution of single nucleotide polymorphism in this gene amongst whites and hispanics | 22695173 |
| 2010-09-16 14:00:00 | Cloning of proSAAS homologs in Danio and Xenopus identifies conserved, putatively functional areas. | 18948394 |
| 2010-01-21 00:00:00 | although both proSAAS and 7B2 potently inhibit PC enzymes via a C-terminal peptide, their intracellular interactions with PCs appear to differ significantly, with each binding protein exhibiting unique properties | 11719503 |
| 2010-01-21 00:00:00 | ProSAAS or proSAAS-like molecules are trapped within tau fibrils and accumulate in tau inclusions in patients with Alzheimer's disease and parkinsonism-dementia complex. | 14746899 |
| Type | IDs |
|---|---|
| Synonymous | BigLEN, PEN, PROSAAS, SAAS, SCG8, SgVIII |
| Gene |
UniProtKB-ID:
PCS1N_HUMAN
UniprotKB:
Q9UHG2
UniParc:
UPI000003778D
EMBL:
BC002851,
AF181562
Ensembl:
ENSG00000102109
KO:
hsa:27344
|
| Nucleutide sequences |
EMBL-CDS:
AAH02851.1,
AAF22643.1
Ensembl_TRS:
ENST00000218230
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000218230
RefSeq:
NP_037403.1
|
| Others |
UniRef100:
UniRef100_Q9UHG2
UniRef90:
UniRef90_Q9UHG2
UniRef50:
UniRef50_Q9UHG2
UniGene:
Hs.522640
CCDS:
CCDS14307.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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