| Type | Description |
|---|---|
| Definition | trinucleotide repeat containing adaptor 6A |
| Date | Results | Publications |
|---|---|---|
| 2020-08-22 15:25:00 | Expression of TNRC6 (GW182) Proteins Is Not Necessary for Gene Silencing by Fully Complementary RNA Duplexes. | 31670606 |
| 2019-12-14 11:29:00 | we report the important roles of GW182 and DDX6, but not Dicer, Ago2 and DCP1A, in PB formation, and that Kaposi's sarcoma-associated herpesvirus (KSHV) lytic infection reduces PB formation through several specific interactions with viral RNA-binding protein ORF57 | 31400113 |
| 2019-11-23 10:40:00 | Study results demonstrate that TNRC6A regulates the biogenesis of the circRNA circ0006916, which regulates lung cancer cells proliferation by binding to miR-522-3p and inhibiting PHLPP1 activity. | 29726904 |
| 2019-08-24 11:59:00 | The structure of GW182 protein silencing domain, including RNA recognition motif. | 29080206 |
| 2019-03-30 11:37:00 | Besides the role of GW182 as part of repressor complexes inside the cell, they function in wide variety of cellular processes including pathogenesis, circadian rhythm and cell cycle. (Review) | 29791863 |
| Type | IDs |
|---|---|
| Synonymous | CAGH26, FAME6, GW1, GW182, TNRC6 |
| Gene |
UniProtKB-ID:
TNR6A_HUMAN
UniprotKB:
Q8NDV7
UniParc:
UPI00019B222B,
UPI00019B222A,
UPI0000351555,
UPI000155D53E,
UPI000006DE91,
UPI000059D33E
EMBL:
AC002565,
AY035864,
BC024324,
AJ492221,
U80739,
AC008731,
AK001773,
AB040893,
BC068209,
AL833757,
AL713750
Ensembl:
ENSG00000288130,
ENSG00000090905
KO:
hsa:27327
|
| Nucleutide sequences |
EMBL-CDS:
CAD28525.2,
CAH56236.1,
BAA95984.1,
AAB91438.1,
CAD37348.1,
BAA91899.1,
AAH24324.2,
AAK62026.1
Ensembl_TRS:
ENST00000672933,
ENST00000395799,
ENST00000673084,
ENST00000315183
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000326900,
ENSP00000379144,
ENSP00000500873,
ENSP00000500125
RefSeq:
NP_001317449.1,
XP_024305999.1,
XP_016878643.1,
XP_005255314.1,
XP_016878642.1,
XP_016878634.1,
XP_016878635.1,
NP_001338779.1,
NP_055309.2,
XP_016878637.1,
XP_016878633.1,
XP_024306001.1,
XP_024306000.1,
XP_016878641.1,
XP_016878639.1
|
| Others |
UniRef100:
UniRef100_Q8NDV7
UniRef90:
UniRef90_Q8NDV7
UniRef50:
UniRef50_Q8NDV7
UniGene:
Hs.655057
CCDS:
CCDS81959.1,
CCDS10624.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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