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27292 DIMT1

27292

DIMT1

DIMT1, rRNA methyltransferase and ribosome maturation factor

protein-coding

Homo sapiens

基因描述

Type Description
Definition DIMT1, rRNA methyltransferase and ribosome maturation factor

研究结论

Date Results Publications
2021-01-23 13:01:00 Structural and catalytic roles of the human 18S rRNA methyltransferases DIMT1 in ribosome assembly and translation. 32616653
2018-10-20 10:42:00 DIMT1 is overexpressed in gastric carcinoma and is significantly correlated with poor prognosis. 28601661
2017-09-30 12:00:00 Studies show that miroRNA miR-210 acts as a tumor suppressor in hypoxic conditions by downregulating the 18S rRNA base methyltransferase (DIMT1)-interferon regulatory factor 4 (IRF4) axis. 28164410
2016-03-12 11:11:00 DIMT1L and WBSCR22-TRMT112 are required for distinct pre-rRNA processing reactions leading to synthesis of 18S rRNA. Ribosome biogenesis requires the presence of the modification enzyme rather than its RNA-modifying catalytic activity. 25851604
2015-10-31 11:25:00 Epigenetic silencing of miR-210 increases the proliferation of gastric epithelium during chronic Helicobacter pylori infection by activating STMN1 and DIMT1. 25187177

名称对应

Type IDs
Synonymous DIM1, DIMT1L, HSA9761, HUSSY5
Gene
UniProtKB-ID: DIM1_HUMAN, A8K9K8_HUMAN, A0A0C4DGB1_HUMAN
UniprotKB: Q9UNQ2, A8K9K8, A0A0C4DGB1
UniParc: UPI00001293E2, UPI00015DAA33, UPI00000727E9
EMBL: AJ009761, AF091078, AK292723, BC010874, AF102147, AC016637, BC002841
Ensembl: ENSG00000086189
KO: hsa:27292
Nucleutide sequences
EMBL-CDS: CAA08815.1, AAC97955.1, AAC72947.1, AAH10874.1, AAH02841.1, BAF85412.1
Gene_ORFName: HUSSY-05
Ensembl_TRS: ENST00000199320, ENST00000506390
Protein sequencees
Ensembl_PRO: ENSP00000199320, ENSP00000421754
RefSeq: NP_055288.1, NP_001335006.1, NP_001335005.1
Others
UniRef100: UniRef100_A8K9K8, UniRef100_Q9UNQ2, UniRef100_A0A0C4DGB1
UniRef90: UniRef90_A0A0C4DGB1, UniRef90_Q9UNQ2
UniRef50: UniRef50_Q9UNQ2, UniRef50_A0A0C4DGB1
UniGene: Hs.731665
CCDS: CCDS3981.1

全选

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