| Type | Description |
|---|---|
| Definition | vacuolar protein sorting 4 homolog A |
| Date | Results | Publications |
|---|---|---|
| 2021-01-16 16:00:00 | VPS4A Mutations Cause Multisystem Disease with Abnormal Neurodevelopment. | 33186545 |
| 2021-01-16 16:00:00 | VPS4A Mutations in Humans Cause Syndromic Congenital Dyserythropoietic Anemia due to Cytokinesis and Trafficking Defects. | 33186543 |
| 2020-05-02 11:52:00 | Vps4A regulates the plasma membrane localization and exosome sorting of beta-catenin, consequently decreasing beta-catenin signaling, and thereby inhibiting epithelial mesenchymal transformation and metastasis in hepatocellular carcinoma. | 31059752 |
| 2019-11-30 10:39:00 | Visualization of IST1 structures in cells lacking the microtubule-severing enzyme spastin and in cells depleted of specific ESCRT-III components or the ATPase VPS4 demonstrated the contribution of these components to the organization and function of ESCRTs in cells. | 30110633 |
| 2018-11-17 10:04:00 | These results demonstrate that the ESCRT machinery, and in particular VPS4, plays a critical role in the early stages of PV infection. | 28349933 |
| Type | IDs |
|---|---|
| Synonymous | SKD1, SKD1A, SKD2, VPS4, VPS4-1 |
| Gene |
UniProtKB-ID:
VPS4A_HUMAN,
A0A024R705_HUMAN
UniprotKB:
Q9UN37,
A0A024R705
UniParc:
UPI000000DC7F
EMBL:
AF155740,
AF159063,
CH471092,
AF255952,
AF112215,
AK315026,
AF282903,
AF132747,
BC047932
Ensembl:
ENSG00000132612
KO:
hsa:27183
|
| Nucleutide sequences |
EMBL-CDS:
AAG01470.1,
AAL75948.1,
AAH47932.1,
BAG37514.1,
AAF17203.1,
AAK52408.1,
AAD42971.1,
EAW83263.1,
AAD49227.1,
EAW83264.1
Gene_ORFName:
hCG_28199
Ensembl_TRS:
ENST00000254950
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000254950
RefSeq:
NP_037377.1
|
| Others |
UniRef100:
UniRef100_Q9UN37
UniRef90:
UniRef90_Q9UN37
UniRef50:
UniRef50_Q9UN37
UniGene:
Hs.128420
CCDS:
CCDS45517.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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