| Type | Description |
|---|---|
| Definition | T cell leukemia, homeobox 3 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-28 10:51:00 | Ectopic expression of TLX3 alone caused partially penetrant leukemia. TLX3 expression and loss of PHF6 combined caused fully penetrant early-onset leukemia. | 30755422 |
| 2018-04-14 11:42:00 | These results demonstrate a novel role for Tlx3 and indicate that Pax6-Tlx3 expression and interaction is part of a region specific regulatory network in cerebellum and its deregulation during development could possibly lead to Autistic spectral disorders (ASD). | 27452274 |
| 2016-05-14 11:46:00 | Tlx3 promotes glutamatergic neuronal subtype specification through direct interactions with the chromatin modifier CBP. | 26258652 |
| 2015-01-17 12:45:00 | Tlx3 uses distinct mechanisms to tightly modulate Prrxl1 activity, either by controlling its transcriptional levels or by increasing Prrxl1 phosphorylation state. | 25138281 |
| 2013-12-07 11:54:00 | The tlx2 knockout mice failed to exhibit escape response evoked by dynamic mechanical stimuli but retained the ability to sense innocuous cooling and/or warm and development of a subset of excitatory neurons located in laminae I and II was impaired. | 24027274 |
| Type | IDs |
|---|---|
| Synonymous | Hox11l2, Rnx, Tlx1l2 |
| Gene |
UniProtKB-ID:
TLX3_MOUSE
UniprotKB:
O55144
UniParc:
UPI0000193590
EMBL:
CH466604,
AL772409,
BC141308,
AJ223801,
BC145631,
AK141870
Ensembl:
ENSMUSG00000040610
KO:
mmu:27140
|
| Nucleutide sequences |
EMBL-CDS:
AAI45632.1,
BAE24864.1,
EDL23743.1,
AAI41309.1,
CAA11551.1
Ensembl_TRS:
ENSMUST00000037746
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000047457
RefSeq:
XP_036012630.1,
NP_064300.2
|
| Others |
UniRef100:
UniRef100_O55144
UniRef90:
UniRef90_O43711
UniRef50:
UniRef50_O43711
UniGene:
Mm.25362
CCDS:
CCDS24533.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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