| Type | Description |
|---|---|
| Definition | eukaryotic translation initiation factor 2 alpha kinase 4 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-22 15:28:00 | Activation of GCN2/ATF4 signals in amygdalar neurons promotes WAT browning under leucine deprivation. | 32504036 |
| 2020-07-18 12:32:00 | These findings indicated that GCN2 suppression alleviated apoptosis and endoplasmic reticulum stress in cerebral ischemia through reducing FoxO3a-dependent reactive oxygen species production. | 31255283 |
| 2020-06-20 11:16:00 | Our results reveal a novel role of GCN2 in TH9 cell differentiation | 31121187 |
| 2020-05-30 12:01:00 | The eukaryotic translation initiation factor 2alpha (eIF2alpha) kinase GCN2 is activated by amino acid starvation to elicit a rectifying physiological program known as the Integrated Stress Response (ISR). | 31749445 |
| 2020-04-18 12:09:00 | Hepatic GCN2 controls FGF21 secretion under a low-protein diet and modulates a whole body postprandial oxidation profile. | 31573843 |
| Type | IDs |
|---|---|
| Synonymous | 2610011M03, GCN2, MGCN2 |
| Gene |
UniProtKB-ID:
E2AK4_MOUSE,
A2AUM0_MOUSE
UniprotKB:
Q9QZ05,
A2AUM0
UniParc:
UPI0000020E70,
UPI00004E193A,
UPI00004E193B,
UPI00004E1939,
UPI00004E187F,
UPI00000E9C1F,
UPI00004E193C
EMBL:
AK077199,
AK013758,
BC072637,
AK129334,
AF193343,
AJ243533,
AF193342,
AL929163,
AF193344,
AK011380,
BC023958
Ensembl:
ENSMUSG00000005102
KO:
mmu:27103
|
| Nucleutide sequences |
EMBL-CDS:
AAG22590.1,
BAC98144.2,
CAB58363.1,
BAB28984.1,
AAG22591.1,
BAB27580.1,
AAH72637.1,
BAC36677.1,
AAH23958.1,
AAG22589.1
Ensembl_TRS:
ENSMUST00000110869,
ENSMUST00000110870,
ENSMUST00000102527,
ENSMUST00000005233
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000106494,
ENSMUSP00000099586,
ENSMUSP00000106493,
ENSMUSP00000005233
RefSeq:
XP_036018145.1,
NP_001342312.1,
XP_006499688.1,
NP_001171277.1,
NP_038747.2,
XP_017174398.1,
XP_006499690.1,
XP_006499689.1
|
| Others |
UniRef100:
UniRef100_Q9QZ05,
UniRef100_A2AUM0
UniRef90:
UniRef90_Q9QZ05
UniRef50:
UniRef50_Q9QZ05
UniGene:
Mm.217616
CCDS:
CCDS50669.1,
CCDS16576.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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