| Type | Description |
|---|---|
| Definition | N-methylpurine-DNA glycosylase |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:26:00 | Alkyladenine DNA glycosylase deficiency uncouples alkylation-induced strand break generation from activation and glycolysis inhibition. | 32042007 |
| 2019-11-30 11:19:00 | ZEB1 promotes colitis and inflammatory CRC through the inhibition of MPG in epithelial cells, thus offering new therapeutic strategies to modulate inflammation and inflammatory cancer | 31366457 |
| 2017-04-08 10:24:00 | The depletion of Aag did not significantly change the transcriptional inhibitory or mutagenic properties of all five examined lesions, suggesting a negligible role of Aag in the repair of these DNA adducts in mammalian cells. | 26930515 |
| 2016-01-16 10:45:00 | This study demonstrates for the first time a non-linear dose-response for alkylation-induced colorectal carcinogenesis and reveals DNA repair by MGMT, but not AAG, as a key node in determining a carcinogenic threshold. | 26243310 |
| 2015-04-18 10:57:00 | the detrimental effects of Aag-initiated BER during I/R and sterile inflammation, and present a novel target for controlling I/R-induced injury. | 25349415 |
| Type | IDs |
|---|---|
| Synonymous | 9830006D05, AI326268, APNG, Aag, Mid1 |
| Gene |
UniProtKB-ID:
3MG_MOUSE
UniprotKB:
Q04841
UniParc:
UPI00000218B4
EMBL:
X74509,
BC014754,
X75040,
S81120,
S81162,
U10420,
AL929446,
S81134,
M99625,
S81133,
X75039,
X75038
Ensembl:
ENSMUSG00000020287
KO:
mmu:268395
|
| Nucleutide sequences |
EMBL-CDS:
AAA02577.1,
AAA19487.1,
CAA52615.1,
AAH14754.1
Ensembl_TRS:
ENSMUST00000020528
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000020528
RefSeq:
NP_034952.2
|
| Others |
UniRef100:
UniRef100_Q04841
UniRef90:
UniRef90_Q04841
UniRef50:
UniRef50_P29372
UniGene:
Mm.263161,
Mm.491092
CCDS:
CCDS24520.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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