| Type | Description |
|---|---|
| Definition | integrin subunit beta 1 binding protein 2 |
| Date | Results | Publications |
|---|---|---|
| 2017-05-16 08:53:00 | Studies in mouse show that melusin prevents cardiac dilation during chronic pressure overload by specifically sensing mechanical stress. | 12496958 |
| 2013-03-02 10:52:00 | Chp-1 and melusin can interact with cochaperones PP5 and Sgt1 and with each other in an ATP-dependent manner | 23184943 |
| 2013-02-02 11:57:00 | Identification of a missense mutation in the melusin-encoding ITGB1BP2 gene in a patient with dilated cardiomyopathy | 23124043 |
| 2012-06-02 11:09:00 | The altered melusin pathways and CDC42 parallel the cardiac function progression during cardiac remodeling post-MI. | 21546274 |
| 2010-04-19 12:01:00 | Our analysis revealed an extremely low number of variations in the ITGB1BP2 gene in nearly 1000 hypertensive/cardiopathic and healthy individuals, thus suggesting a high degree of conservation of the melusin gene within the populations analyzed | 20017903 |
| Type | IDs |
|---|---|
| Synonymous | CHORDC3, ITGB1BP, MELUSIN, MSTP015 |
| Gene |
UniProtKB-ID:
ITBP2_HUMAN
UniprotKB:
Q9UKP3
UniParc:
UPI00005DC728,
UPI000000103C
EMBL:
AF110225,
BC108901,
AL590762,
AF140690
Ensembl:
ENSG00000147166
KO:
hsa:26548
|
| Nucleutide sequences |
EMBL-CDS:
AAL36913.1,
AAF01676.1,
AAI08902.1
Gene_ORFName:
MSTP015
Ensembl_TRS:
ENST00000373829,
ENST00000538820
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000440289,
ENSP00000362935
RefSeq:
NP_001290206.1,
NP_036410.1
|
| Others |
UniRef100:
UniRef100_Q9UKP3
UniRef90:
UniRef90_Q9UKP3
UniRef50:
UniRef50_Q9UKP3
UniGene:
Hs.109999
CCDS:
CCDS14411.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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