| Type | Description |
|---|---|
| Definition | control protein E1A;control protein E1A 243R |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:24:00 | Differential Effects of Human Adenovirus E1A Protein Isoforms on Aerobic Glycolysis in A549 Human Lung Epithelial Cells. | 32503156 |
| 2020-05-02 10:20:00 | The authors found differential expression of the NAD-dependent CtBP protein homologs between lymphocytes and epithelial cells, and inhibition of CtBP complexes upregulates adenovirus E1A expression in T lymphocyte cell lines but not in lytically-infected epithelial cells. | 31864392 |
| 2018-08-25 10:57:00 | The functions of Adenovirus E1A C-terminal interactions with human FOXK, DCAF7, and CtBP are unknown. The authors found that these interactions modulate RAS signaling, and that a single e1a molecule must bind all three of these host proteins to suppress activation of a subset of interferon-stimulated genes (ISGs). | 29241042 |
| 2017-06-24 11:34:00 | Ku70 (XRCC6) was found to bind directly within the CR4 of E1A from human adenovirus type 5. | 27769014 |
| 2017-05-20 10:37:00 | Adenovirus E1A was found to bind to RuvBL1 via the C terminus of E1A, and this interaction was important for suppression of interferon-stimulated gene transcriptional activation and recruitment of E1A to interferon-regulated promoters. | 28122980 |
| Type | IDs |
|---|---|
| Synonymous | HAdVCgp01 |
| Gene |
UniProtKB-ID:
J9Z5B4_9ADEN,
J9Z4C8_9ADEN
UniprotKB:
J9Z5B4,
J9Z4C8
UniParc:
UPI0000163761,
UPI00000F0477
EMBL:
MH121086,
MH121101,
KF268310,
KF268130,
KR699642,
JX173077,
MK883607,
MH121102,
KF951595,
JX173079
KO:
vg:2652980
|
| Nucleutide sequences |
EMBL-CDS:
QJX16247.1,
AZR67347.1,
ALK80082.1,
AZR67311.1,
AZR66778.1,
AGT75965.1,
AFS50219.1,
AGT77055.1,
AHN92649.1,
AFS50311.1,
AHN92650.1,
AGT77056.1,
AGT75966.1,
AFS50312.1,
AFS50220.1
Gene_ORFName:
H648_34933gpE1A,
H648_42032gpE1A,
H648_34617gpE1A,
H648_34615gpE1A,
H648_42032gpE1A,
H648_34933gpE1A,
H648_34615gpE1A,
H648_34617gpE1A
|
| Protein sequencees |
RefSeq:
NP_040507.1,
NP_040508.1
|
| Others |
UniRef100:
UniRef100_E1U5L4,
UniRef100_E1U5L3
UniRef90:
UniRef90_P03255
UniRef50:
UniRef50_P03255
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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