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2615 LRRC32

2615

LRRC32

leucine rich repeat containing 32

protein-coding

Homo sapiens

基因描述

Type Description
Definition leucine rich repeat containing 32

研究结论

Date Results Publications
2021-01-30 13:02:00 Thrombin contributes to cancer immune evasion via proteolysis of platelet-bound to activate LTGF-beta. 31915300
2020-10-24 14:01:00 Novel biomarkers for primary biliary cholangitis to improve diagnosis and understand underlying regulatory mechanisms. 31033124
2020-06-20 10:54:00 Data indicate homozygous stop-gain variant in leucine rich repeat containing 32 protein (LRRC32) (c.1630C>T; p.(Arg544Ter)) as a candidate disease-associated gene in two families with developmental delay, cleft palate, and proliferative retinopathy. 30976112
2020-01-11 10:47:00 Our findings reveal that as an immunoregulatory molecule, is located on, as well as in, tumor cells of GB and low-grade glioma, inhibiting effector T cell function, and thus contributing to the immunosuppressive tumor microenvironment of primary brain tumors. 31357555
2019-11-30 12:28:00 Study demonstrated that B cells are required for the induction of oral tolerance of T cell-dependent antigens via and revealed for the first time that cell surface is an important checkpoint for regulating B cell peripheral tolerance, highlighting a mechanism of autoimmune disease pathogenesis. 29618665

名称对应

Type IDs
Synonymous D11S833E, GARP
Gene
UniProtKB-ID: LRC32_HUMAN, A0A024R5J7_HUMAN
UniprotKB: Q14392, A0A024R5J7
UniParc: UPI000012B0DF
EMBL: CH471076, Z24680, BC052210, BC070079
Ensembl: ENSG00000137507
KO: hsa:2615
Nucleutide sequences
EMBL-CDS: CAA80847.1, AAH70079.1, AAH52210.2, EAW75001.1, EAW75002.1
Gene_ORFName: hCG_40444
Ensembl_TRS: ENST00000260061, ENST00000407242, ENST00000404995
Protein sequencees
Ensembl_PRO: ENSP00000384126, ENSP00000385766, ENSP00000260061
RefSeq: NP_001357117.1, NP_001357120.1, NP_001122394.1, XP_011543237.1, NP_005503.1, NP_001357116.1, NP_001357118.1, NP_001357119.1
Others
UniRef100: UniRef100_Q14392
UniRef90: UniRef90_Q14392
UniRef50: UniRef50_Q14392
UniGene: Hs.151641
CCDS: CCDS8245.1

全选

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研究热度

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