| Type | Description |
|---|---|
| Definition | G protein subunit alpha i1 |
| Date | Results | Publications |
|---|---|---|
| 2017-09-30 13:41:00 | Data suggest that Gnai1 subunit of GTP-binding protein catalyzes nucleotide exchange by selective perturbance of GDP-bound conformation of Gnai1 to metastable intermediate structural state and accelerates rate-limiting step of GDP release by surpassing kinetic barrier. | 28627018 |
| 2017-06-24 10:10:00 | Induction of Galphai1 structural heterogeneity by Ric-8A provides a mechanism for nucleotide release | 27558716 |
| 2017-05-27 11:55:00 | Molecular dynamics simulation of a myristoylated G protein subunit alpha i1 (Galphai1)-GTP complex suggests that the myristoyl-induced conformational changes of the switch II and alpha helical domains create new possibilities for protein-protein interactions. | 27936598 |
| 2016-05-21 12:11:00 | stimulation of GPR17 by the small molecule agonist MDL29,951 (2-carboxy-4,6-dichloro-1H-indole-3-propionic acid) decreases myelin basic protein expression levels mainly by triggering the Galphai/o signaling pathway. | 26620557 |
| 2015-12-05 11:07:00 | These results in part explain the mobility of Galphai1 protein upon reversible palmitoylation to meet one or another type of signaling protein partner. | 26253820 |
| Type | IDs |
|---|---|
| Synonymous | BPGTPB |
| Gene |
UniProtKB-ID:
GNAI1_RAT
UniprotKB:
P10824
UniParc:
UPI0000167A2B
EMBL:
M17527,
DQ120470,
DQ120469
Ensembl:
ENSRNOG00000057096
KO:
rno:25686
|
| Nucleutide sequences |
EMBL-CDS:
AAA40825.1,
AAZ23808.1,
AAZ23809.1
Ensembl_TRS:
ENSRNOT00000091004
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000074036
RefSeq:
NP_037277.1
|
| Others |
UniRef100:
UniRef100_P10824
UniRef90:
UniRef90_P08754
UniRef50:
UniRef50_P08754
UniGene:
Rn.11391
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| 1 |
University of Texas Southwestern Medical Center |
5 |
| 2 |
Howard Hughes Medical Institute |
5 |
| 3 |
Emory University School of Medicine |
3 |
| 4 |
University of Montreal |
3 |
| 5 |
Rockefeller University |
2 |
| 排名 | 研究人员 | 文献 |
|---|---|---|
| 1 |
S R Sprang |
7 |
| 2 |
A G Gilman |
6 |
| 3 |
E Lee |
4 |
| 4 |
Gregory G Tall |
4 |
| 5 |
D E Coleman |
3 |