| Type | Description |
|---|---|
| Definition | FKBP prolyl isomerase 1A |
| Date | Results | Publications |
|---|---|---|
| 2018-07-14 10:45:00 | FKBP12 can endogenously regulate calcineurin activity with therapeutic implications for the treatment of Parkinson's Disease. | 29229832 |
| 2012-06-30 10:53:00 | The effects of FKBP12.6 and another structurally similar molecule, FKBP12, which is far more abundant in heart, on the gating of single sheep RyR2 channels, were investigated. | 22363773 |
| 2011-03-05 10:42:00 | FKBP12 regulates H-Ras trafficking by promoting depalmitoylation through cis-trans isomerization of a peptidyl-prolyl bond in proximity to the palmitoylated cysteines. | 21255728 |
| 2010-01-21 00:00:00 | Data show that K201 abolished spontaneous calcium release in cardiac myocytes, and that treating ventricular myocytes with FK506 to dissociate FKBP12.6 from ryanodine receptor RyR2 did not affect the suppression of spontaneous Ca2+ release by K201. | 17313373 |
| 2010-01-21 00:00:00 | FKBP12 is predominantly present during early neointima formation, while mature neointimal atheromas show a relatively low expression without confinement to luminal areas. | 17962721 |
| Type | IDs |
|---|---|
| Synonymous | FKBP12, Fkbp2 |
| Gene |
UniProtKB-ID:
FKB1A_RAT
UniprotKB:
Q62658
UniParc:
UPI000014B5A0
EMBL:
BC126071,
BC070519,
U69485,
D86641,
U09386
Ensembl:
ENSRNOG00000008822
KO:
rno:25639
|
| Nucleutide sequences |
EMBL-CDS:
AAB48933.1,
BAA13153.1,
AAI26072.1,
AAH70519.3,
AAA19163.1
Ensembl_TRS:
ENSRNOT00000012608
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000012608
RefSeq:
NP_037234.2
|
| Others |
UniRef100:
UniRef100_Q62658
UniRef90:
UniRef90_P26883
UniRef50:
UniRef50_P26883
UniGene:
Rn.80611
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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