| Type | Description |
|---|---|
| Definition | protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 |
| Date | Results | Publications |
|---|---|---|
| 2017-01-28 10:22:00 | PIMT was critical for bFGF-mediated neuronal differentiation of PC12 cells and regulated the MAPK and Akt signaling pathways. | 26973341 |
| 2014-09-20 12:15:00 | ERK2-mediated phosphorylation of transcriptional coactivator binding protein PIMT/NCoA6IP at Ser298 augments hepatic gluconeogenesis. | 24358311 |
| 2010-01-21 00:00:00 | PIMT-KO phenotype results from the cumulative effect of isoaspartate-related damage to a number of the neuron-rich proteins detected in this study | 16959769 |
| 2010-01-21 00:00:00 | isoforms of the PIMT/Tgs1 protein with an RNA methyltransferase domain function both in the nucleus and in the cytoplasm | 12943661 |
| 2010-01-21 00:00:00 | Ethanol consumption results in the accumulation of modified proteins bearing atypical isoaspartyl residues via impaired in vivo PIMT activity, while betaine administration prevents it by restoring the PIMT-catalyzed protein repair reaction | 17336420 |
| Type | IDs |
|---|---|
| Synonymous | PCM |
| Gene |
UniProtKB-ID:
PIMT_RAT
UniprotKB:
P22062
UniParc:
UPI00004A050D
EMBL:
D11475,
BC088417,
M26686
KO:
rno:25604
|
| Nucleutide sequences |
EMBL-CDS:
AAA60742.1,
AAH88417.1,
BAA02034.1
|
| Protein sequencees |
RefSeq:
NP_037205.2
|
| Others |
UniRef100:
UniRef100_P22062
UniRef90:
UniRef90_P22061
UniRef50:
UniRef50_P22061
UniGene:
Rn.86985
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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