| Type | Description |
|---|---|
| Definition | alkaline phosphatase, biomineralization associated |
| Date | Results | Publications |
|---|---|---|
| 2021-01-16 15:59:00 | TNAP inhibition attenuates cardiac fibrosis induced by myocardial infarction through deactivating TGF-beta1/Smads and activating P53 signaling pathways. | 31969558 |
| 2018-01-06 10:52:00 | he rats body weight were decreased, the cartilage histological structure were disrupted, the cartilage and serum contents of Al and the serum level of C-telopeptide of type II collagen were all increased, the serum level of type II collagen (Col II) and alkaline phosphatase (ALP), and the mRNA expressions of TGF-beta1, BMP-2, ALP and Col II were all decreased in the AlCl3-treated groups compared with those in control g... | 27885436 |
| 2017-06-24 12:19:00 | Data show that nonylphenol (NP) increased serum alkaline phosphatase, lead to liver damage and can increase the expression of heme oxygenase-1 (HO1) and growth arrest and DNA-damage-inducible 45 beta protein (Gadd45b) genes and may modify the toxic effects on liver through induction of oxidative stress. | 27590577 |
| 2015-10-31 11:11:00 | TNAP contributes to the hypertrophic effect of phenylephrine, as well as its ability to produce cardiomyocyte calcification. These responses are minimized by CD73-dependent endogenously produced adenosine. | 24894822 |
| 2015-10-31 11:01:00 | TNAP histochemistry offers a more straightforward, but also more sensitive, method for investigating retinal strata and their diabetes-induced degeneration. | 25411053 |
| Type | IDs |
|---|---|
| Synonymous | Akp2, PHOA |
| Gene |
UniProtKB-ID:
PPBT_RAT
UniprotKB:
P08289
UniParc:
UPI0000132007
EMBL:
Y00714,
X16033,
X16035,
X16029,
X16038,
X16037,
X16032,
X16036,
X16028,
X16031,
X16030,
BC088399,
J03572,
X16034
Ensembl:
ENSRNOG00000013954
KO:
rno:25586
|
| Nucleutide sequences |
EMBL-CDS:
CAA34160.1,
CAA68703.1,
AAA41845.1,
AAH88399.1
Ensembl_TRS:
ENSRNOT00000019004
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000019004
RefSeq:
XP_006239198.1,
XP_017448654.1,
NP_037191.2
|
| Others |
UniRef100:
UniRef100_P08289
UniRef90:
UniRef90_P08289
UniRef50:
UniRef50_P05186-2
UniGene:
Rn.82764
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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