| Type | Description |
|---|---|
| Definition | signal-regulatory protein alpha |
| Date | Results | Publications |
|---|---|---|
| 2012-11-17 10:24:00 | In the glomeruli of CNS patients carrying mutations in NPHS1, where SD formation is disrupted, the expression of SIRPalpha as well as Neph1 and nephrin was significantly decreased, indicating that SIRPalpha is closely associated with the nephrin complex | 22747997 |
| 2012-07-21 11:24:00 | Data suggest that hyperglycemia induces increase in association of SHPS-1 with IAP (integrin-associated protein); this appears to be a generalized response of endothelial cells that contributes to endothelial cell dysfunction. | 22193512 |
| 2012-04-21 12:03:00 | Data demonstrate that BIT/SHPS-1 promotes the antiapoptotic effect of BDNF on the low potassium-induced cell death of cerebellar granule neuronss. | 21553247 |
| 2011-06-04 11:26:00 | Data show that myelin down-regulates its own phagocytosis through CD47-SIRPalpha interactions. | 21401967 |
| 2010-09-27 11:09:00 | CD47-SIRP-alpha interaction may be functionally important in cell-cell communication in the diseased glomerulus. | 20554646 |
| Type | IDs |
|---|---|
| Synonymous | Bit, Ptpns1, SHPS-1 |
| Gene |
UniProtKB-ID:
SHPS1_RAT,
Q499T3_RAT
UniprotKB:
P97710,
Q499T3
UniParc:
UPI00000E8791,
UPI000056EE25
EMBL:
U62328,
AABR07053715,
BC099773,
D85183,
AF055065,
D38468
Ensembl:
ENSRNOG00000004763
KO:
rno:25528
|
| Nucleutide sequences |
EMBL-CDS:
BAA20368.1,
BAA12734.1,
AAC68478.1,
AAC18089.1,
AAH99773.1
Ensembl_TRS:
ENSRNOT00000006408,
ENSRNOT00000091935
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000006408,
ENSRNOP00000069024
RefSeq:
XP_006235013.1,
XP_017446986.1,
XP_006235014.1,
XP_006235015.1,
XP_017446985.1,
XP_017446987.1,
NP_037148.3
|
| Others |
UniRef100:
UniRef100_P97710,
UniRef100_Q499T3
UniRef90:
UniRef90_P97710
UniRef50:
UniRef50_P78324
UniGene:
Rn.53971
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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