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25508 Pam

25508

Pam

peptidylglycine alpha-amidating monooxygenase

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition peptidylglycine alpha-amidating monooxygenase

研究结论

Date Results Publications
2015-12-12 10:09:00 Disruption of AP-1-dependent late endosomal trafficking diminishes the ability of PAM to retain copper and produce amidated peptides. 26170456
2014-08-09 12:26:00 Data indicate that H3A mutation eliminates the ability of internalized peptidylglycine alpha-amidating monooxygenase PAM-1 to return to secretory granules. 24627494
2013-07-27 11:55:00 The crystal structure of the oxidized form of PHM complexed with hydrogen peroxide. 23247335
2010-01-21 00:00:00 the structure of the ternary complex of the peptidylglycine-alphahydroxylating monooxygenase (PHM) domain of PAM with molecular oxygen and a peptide that contains a D-amino acid designed to trap the precatalytic complex is presented 15131304
2010-01-21 00:00:00 the appearance of integral membrane PAM at the plasma membrane was stimulated along with hormone secretion in anterior pituitary 15905171

名称对应

Type IDs
Synonymous PHM
Gene
UniProtKB-ID: AMD_RAT
UniprotKB: P14925
UniParc: UPI000002A3AD, UPI000002A3AB, UPI000002A3AC, UPI0000125965, UPI000002A3AF, UPI000002A3B0, UPI000002A3AE
EMBL: U52639, U52658, U52660, U52662, U52641, U52656, M25732, U52648, U52652, U52650, U52663, U52649, U52664, U52659, U52661, U52640, U52653, M63662, U52655, U52645, U52647, U52643, U52642, M25719, U52654, U52646, X59686, M82845, U52657, X59687, X59689, U52644, U52651, X59685, X59688
Ensembl: ENSRNOG00000033280
KO: rno:25508
Nucleutide sequences
EMBL-CDS: CAA42208.1, AAC05603.1, AAA41804.1, AAC05607.1, CAA42209.1, AAC05605.1, AAC05604.1, AAC05606.1, AAC05602.1, AAA41803.1, CAA42206.1, CAA42207.1, CAA42210.1, AAB00162.1, AAA42068.1, AAC05608.1
Ensembl_TRS: ENSRNOT00000056457, ENSRNOT00000043451, ENSRNOT00000041418
Protein sequencees
Ensembl_PRO: ENSRNOP00000046774, ENSRNOP00000053295, ENSRNOP00000050784
RefSeq: XP_017451777.1, XP_017451776.1, XP_006245658.1, XP_006245660.1, NP_037132.2, XP_006245661.1, XP_017451775.1, XP_006245656.1, XP_006245657.1, XP_008765582.1, XP_006245659.1
Others
UniRef100: UniRef100_P14925
UniRef90: UniRef90_P14925
UniRef50: UniRef50_P14925
UniGene: Rn.1121

全选

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