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2542757 rad32

2542757

rad32

Rad32 nuclease

protein-coding

Schizosaccharomyces pombe

基因描述

Type Description
Definition Rad32 nuclease

研究结论

Date Results Publications
2017-07-15 11:54:00 a mre11 mutant defective in endonucleolytic activity, the same mutant lacking Ctp1, or the triple mutant also lacking the putative hairpin nuclease Pso2 showed wild-type levels of repair. Thus, MRN (Mre11-Rad50-Nbs1)may act to recruit the hairpin opening activity that allows subsequent repair 28292918
2010-08-23 11:43:00 Mre11-Rad50-Nbs1 participates in checkpoint-dependent replication slowing through negative regulation of recombination. 20065069
2010-01-21 00:00:00 The conserved Mre11/Rad50/Nbs1 (MRN) complex is likely directly involved in processing palindromes through the homologous recombination pathway of DNA repair. [Mre11] 15654094
2010-01-21 00:00:00 Rad32 nuclease has the catalytic site for Rec12-oligonucleotide generation and is activated by Ctp1, which plays an additional role in meiotic recombination. 19752195
2010-01-21 00:00:00 The Mre11-Rad50-Nbs1 S-phase checkpoint role is separate from its Ctp1- and resection-dependent role in double-strand break repair. 19211838

名称对应

Type IDs
Synonymous mre11
Gene
UniProtKB-ID: RAD32_SCHPO
UniprotKB: Q09683
UniParc: UPI0000133025
EMBL: CU329670, X82322
EnsemblGenome: SPAC13C5.07
KO: spo:SPAC13C5.07
Nucleutide sequences
EMBL-CDS: CAA90458.1, CAA57765.1
Gene_ORFName: SPAC13C5.07
EnsemblGenome_TRS: SPAC13C5.07.1
Protein sequencees
EnsemblGenome_PRO: SPAC13C5.07.1:pep
RefSeq: NP_592935.1
Others
UniRef100: UniRef100_Q09683
UniRef90: UniRef90_Q09683
UniRef50: UniRef50_Q09683

全选

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研究热度

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