| Type | Description |
|---|---|
| Definition | CD59 molecule |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:31:00 | Coenzyme Q10 attenuates rat hepatocarcinogenesis via the reduction of CD59 expression and phospholipase D activity. | 31989689 |
| 2020-05-30 12:01:00 | study thus proposes the previously undescribed existence of non-GPI-anchored cytosolic CD59, which is required for insulin secretion. | 31412214 |
| 2017-12-23 12:07:00 | Study generated CD59(-/-) rats to investigate the role of CD59 in neuromyelitis optica spectrum disorders (NMO) and to create NMO pathology by passive transfer of AQP4-IgG. Results implicate an important role of CD59 in modulating NMO pathology in rats and demonstrate amplification of AQP4-IgG-induced NMO disease with CD59 knockout. | 28212662 |
| 2017-12-23 12:06:00 | Organ injury in neuromyelitis optica (NMO) seropositive CD59(-/-) rats was prevented by a complement inhibitor. Significant pathological changes in seropositive CD59(-/-) rats were not seen in optic nerve, spinal cord or brain, including circumventricular tissue. Results implicate a major protective role of CD59 outside of the central nervous system in seropositive NMO. | 28750658 |
| 2010-01-21 00:00:00 | In rats, CD59 and DAF genes are related to the negative effect of sulfasalazine on sperm maturation. | 17166698 |
| Type | IDs |
|---|---|
| Synonymous | Cd59a, Cd59b, MAC-IP, MACIF, MACIP |
| Gene |
UniProtKB-ID:
CD59_RAT
UniprotKB:
P27274
UniParc:
UPI0000127389
EMBL:
BC063176,
U48255
Ensembl:
ENSRNOG00000042821
KO:
rno:25407
|
| Nucleutide sequences |
EMBL-CDS:
AAA88909.1,
AAH63176.1
Ensembl_TRS:
ENSRNOT00000067085
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000060967
RefSeq:
NP_037057.1
|
| Others |
UniRef100:
UniRef100_P27274
UniRef90:
UniRef90_P27274
UniRef50:
UniRef50_P27274
UniGene:
Rn.1231
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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