| Type | Description |
|---|---|
| Definition | CtIP family endonuclease |
| Date | Results | Publications |
|---|---|---|
| 2019-05-11 11:54:00 | an important role for Ctp1-regulated DNA strand coordination required for DNA DSB repair in S. pombe | 30626735 |
| 2017-11-18 11:21:00 | CtIP/Ctp1/Sae2/Com1 role in removal of DNA double strand breaks through DSB repair by homologous recombination is reviewed. | 28623092 |
| 2017-07-15 11:54:00 | a mre11 mutant defective in endonucleolytic activity, the same mutant lacking Ctp1, or the triple mutant also lacking the putative hairpin nuclease Pso2 showed wild-type levels of repair. Thus, MRN (Mre11-Rad50-Nbs1)may act to recruit the hairpin opening activity that allows subsequent repair | 28292918 |
| 2015-12-19 11:19:00 | The authors concludes that the intracellular Ctp1 C-terminal portion is essential for clipping, while the N-terminal portion is sufficient for DNA double-strand break end-resection. | 26130711 |
| 2015-04-11 11:53:00 | Tetrameric Ctp1 coordinates DNA binding and DNA bridging in DNA double-strand-break repair. | 25580577 |
| Type | IDs |
|---|---|
| Synonymous | mug38, nip1, slr9 |
| Gene |
UniProtKB-ID:
COM1_SCHPO
UniprotKB:
O74986
UniParc:
UPI00015FED0C
EMBL:
EU168806,
AB363065,
CU329672
EnsemblGenome:
SPCC338.08
KO:
spo:SPCC338.08
|
| Nucleutide sequences |
EMBL-CDS:
CAA19339.2,
BAG16512.1,
ABX10016.1
Gene_ORFName:
SPCC338.08
EnsemblGenome_TRS:
SPCC338.08.1
|
| Protein sequencees |
EnsemblGenome_PRO:
SPCC338.08.1:pep
RefSeq:
NP_588159.2
|
| Others |
UniRef100:
UniRef100_O74986
UniRef90:
UniRef90_O74986
UniRef50:
UniRef50_O74986
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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