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248 ALPI

248

ALPI

alkaline phosphatase, intestinal

protein-coding

Homo sapiens

基因描述

Type Description
Definition alkaline phosphatase, intestinal

研究结论

Date Results Publications
2020-05-16 10:59:00 Study establishes that IAP deficiency in stool is associated with ischemic heart disease (IHD), and a high level of IAP might play a protective role against IHD. 31915470
2018-07-28 11:45:00 Data confirm that, in enterocytes (Caco-2 cells), 1-alpha,25-dihydroxy-vitamin-D3 up-regulates expression of 2 isoforms of IAP, alternative splicing variants. 28931466
2018-02-03 10:52:00 Expressions of human intestinal alkaline phosphatase and sucrase-isomaltase, which are intestinal differentiation markers, were highly enhanced in Caco-2 cells by menaquinone-4. 27865621
2017-08-05 11:47:00 Data indicate alkaline phosphatase (AP) as the primary soluble ectonucleotidase in infants undergoing cardiopulmonary bypass and show decreased capacity to clear AMP when AP activity decreases post-bypass. 27384524
2017-07-22 13:08:00 Intestinal alkaline phosphatase is a major regulator of gut mucosal permeability and appears to work at least partly through improving tight junction protein levels and localization. 27106638

名称对应

Type IDs
Synonymous IAP
Gene
UniProtKB-ID: PPBI_HUMAN, A0A024R4A2_HUMAN
UniprotKB: P09923, A0A024R4A2
UniParc: UPI0000131FFE
EMBL: Y00512, AK313163, J03930, M31008, M19161, CH471063, BC132678, AC068134, M15694
Ensembl: ENSG00000163295
KO: hsa:248
Nucleutide sequences
EMBL-CDS: AAA51705.1, CAA68564.1, AAA51704.1, AAI32679.1, BAG35981.1, AAY24089.1, EAW70997.1, AAA98617.1, AAA51703.1, EAW70998.1
Gene_ORFName: hCG_33449
Ensembl_TRS: ENST00000295463
Protein sequencees
Ensembl_PRO: ENSP00000295463
RefSeq: NP_001622.2
Others
UniRef100: UniRef100_P09923
UniRef90: UniRef90_P09923
UniRef50: UniRef50_P09923
UniGene: Hs.37009
CCDS: CCDS2492.1

全选

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研究热度

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