| Type | Description |
|---|---|
| Definition | arachidonate 15-lipoxygenase type B |
| Date | Results | Publications |
|---|---|---|
| 2020-02-15 13:13:00 | Low 15-LOX-2 expression is associated with lung carcinogenesis. | 31420013 |
| 2020-01-04 12:09:00 | ALOX15B expression and up-regulation in the functional and non-functional pituitary adenomas. | 31288808 |
| 2019-10-05 10:27:00 | we identified a novel role for ALOX15B, and to a lesser extent ALOX15, in cholesterol homeostasis and CCL17 production in human macrophages. | 30197642 |
| 2019-02-09 10:51:00 | Results demonstrate the expression of ALOX15 and ALOX15B in failing as well as in donor hearts. ALOX15/B signaling may play an important role in heart disease, including heart failure. Isolated fibroblasts from all four chambers of the heart expressed ALOX15 as well as ALOX15B, and gene expression levels were further increased under hypoxia. | 30138423 |
| 2017-10-14 13:03:00 | Ca(2+) binding induces major structural changes in the 15-lipoxygenase-2 PLAT domain. | 28809482 |
| Type | IDs |
|---|---|
| Synonymous | 15-LOX-2 |
| Gene |
UniProtKB-ID:
LX15B_HUMAN
UniprotKB:
O15296
UniParc:
UPI0000EE63A7,
UPI00001409B3,
UPI0000140991,
UPI000014099F
EMBL:
AF468051,
AF468053,
AC129492,
AJ305030,
U78294,
AJ305029,
AF149095,
CH471108,
AJ305031,
AF468052,
BC035217,
AJ305028,
BC063647,
AF468054
Ensembl:
ENSG00000179593
KO:
hsa:247
|
| Nucleutide sequences |
EMBL-CDS:
AAB61706.1,
EAW90098.1,
AAL76274.1,
AAL76275.1,
AAL76276.1,
AAH63647.1,
EAW90100.1,
AAL76277.1,
AAD37786.1,
AAH35217.1,
CAC34521.1
Ensembl_TRS:
ENST00000380183,
ENST00000380173,
ENST00000573359
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000369530,
ENSP00000369520,
ENSP00000460332
RefSeq:
NP_001034220.1,
NP_001132.2,
NP_001034219.1
|
| Others |
UniRef100:
UniRef100_O15296
UniRef90:
UniRef90_O15296
UniRef50:
UniRef50_O15296
UniGene:
Hs.111256
CCDS:
CCDS32559.1,
CCDS32558.1,
CCDS11128.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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