| Type | Description |
|---|---|
| Definition | myeloid/lymphoid or mixed-lineage leukemia; translocated to, 6 |
| Date | Results | Publications |
|---|---|---|
| 2012-05-19 10:46:00 | AF17 promotes Dot1a nuclear export and upregulates basal, but not aldosterone-stimulated ENaC expression, leading to an increase in ENaC-mediated Na(+) transport in renal collecting duct cells | 22087315 |
| 2011-08-27 11:28:00 | Af17 deficiency increases sodium excretion and decreases blood pressure. Af17 ss a potential locus for the maintenance of sodium and blood pressure homeostasis. | 21546577 |
| 2011-05-28 11:28:00 | Af17 may be dispensable for normal embryogenesis, hematopoiesis, and animal survival. | 21170927 |
| 2010-01-21 00:00:00 | located within a 185-kb contig surrounding a transgene on chromosome 11 | 12438746 |
| 2010-01-21 00:00:00 | AF17 competes with AF9 to bind Dot1a, decreases Dot1a nuclear expression by possibly facilitating its nuclear export, and relieves Dot1a.AF9-mediated repression of alpha-ENaC and other target genes. | 19864429 |
| Type | IDs |
|---|---|
| Synonymous | AI315037, Af17 |
| Gene |
UniProtKB-ID:
Q3UPK1_MOUSE,
B1AR09_MOUSE,
B1AR10_MOUSE
UniprotKB:
Q3UPK1,
B1AR09,
B1AR10
UniParc:
UPI00005AC1F1,
UPI0000193C0F,
UPI000059DCE2
EMBL:
AL596123,
AK143477
Ensembl:
ENSMUSG00000038437
KO:
mmu:246198
|
| Nucleutide sequences |
EMBL-CDS:
BAE25394.1
Ensembl_TRS:
ENSMUST00000044730,
ENSMUST00000107586
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000045445,
ENSMUSP00000103212
RefSeq:
XP_006533398.1,
XP_036012598.1,
XP_006533396.1,
NP_647472.2,
XP_006533395.1
|
| Others |
UniRef100:
UniRef100_B1AR10,
UniRef100_B1AR09
UniRef90:
UniRef90_B1AR09
UniRef50:
UniRef50_B1AR09
UniGene:
Mm.23685
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 25737280 |
Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt. Genes Dev. Jernej Murn , Kathi Zarnack , Yawei J Yang , Omer Durak , Elisabeth A Murphy , Sihem Cheloufi , Dilenny M Gonzalez , Marianna Teplova , Tomaž Curk , Johannes Zuber , Dinshaw J Patel , Jernej Ule , Nicholas M Luscombe , Li-Huei Tsai , Christopher A Walsh , Yang Shi |
2015-03-01 |
Sf3b3,
Pls3,
Xpo1,
Slc38a1,
Rrn3,
Hat1,
Ogt,
Foxp1,
Atp6v1h,
Pnrc1,
Ppp1r15b,
Pkn2,
Rap1a,
Acat1,
Cse1l,
Abcb7,
Actb,
Prdx3,
Ap1g1,
Arf1,
Arf4,
Arf5,
Arhgap5,
Atp2a2,
Atp5a1,
Atpif1,
Phb2,
Birc6,
Calm1,
Calm2,
Calm3,
Ctnna1,
Ctnnb1,
Cbx3,
Cbx5,
Cct4,
Cct5,
Cct8,
Cdc42,
Copa,
Cox5a,
Cox7a2,
Dpysl2,
Csnk2b,
Ctsb,
Dhx15,
Ddx5,
Dync1h1,
Dst,
Mapre1,
Eef1a1,
Eef2,
Eif3a,
Eif4a1,
Eif4a2,
Eif4g2,
Gdi1,
Gdi2,
Gfpt1,
Ggps1,
Gls,
Glud1,
Rack1,
Pdia3,
H3f3b,
Hdac2,
Hint1,
Hmgcr,
Hn1,
Hnrnpab,
Hnrnpl,
Hspd1,
Hsp90ab1,
Hsp90aa1,
Hspa4,
Hspa9,
Hspe1,
Id3,
Kpnb1,
Eif3e,
Itgb1,
Itm2b,
Kpna4,
Kpna6,
Kras,
Ldha,
Nup155,
Matr3,
Mcl1,
Msh6,
Laptm4a,
Nap1l4,
Ncl,
Nfib,
Ogdh,
Pdcd4,
Slc25a3,
Plaa,
Ppp1cb
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 21677750 |
A conditional knockout resource for the genome-wide study of mouse gene function. Nature William C Skarnes , Barry Rosen , Anthony P West , Manousos Koutsourakis , Wendy Bushell , Vivek Iyer , Alejandro O Mujica , Mark Thomas , Jennifer Harrow , Tony Cox , David Jackson , Jessica Severin , Patrick Biggs , Jun Fu , Michael Nefedov , Pieter J de Jong , A Francis Stewart , Allan Bradley |
2011-06-15 | - |
| 21546577 |
Af17 deficiency increases sodium excretion and decreases blood pressure. J. Am. Soc. Nephrol. Lihe Chen , Hongyu Wu , Oleh M Pochynyuk , Mary Rose Reisenauer , Zhijing Zhang , Le Huang , Oleg Leonidovych Zaika , Mykola Mamenko , Weiru Zhang , Qiaoling Zhou , Mingyao Liu , Yang Xia , Wenzheng Zhang |
2011-06-01 |
Mllt6
|
| 21267068 |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. Graciana Diez-Roux , Sandro Banfi , Marc Sultan , Lars Geffers , Santosh Anand , David Rozado , Alon Magen , Elena Canidio , Massimiliano Pagani , Ivana Peluso , Nathalie Lin-Marq , Muriel Koch , Marchesa Bilio , Immacolata Cantiello , Roberta Verde , Cristian De Masi , Salvatore A Bianchi , Juliette Cicchini , Elodie Perroud , Shprese Mehmeti , Emilie Dagand , Sabine Schrinner , Asja Nürnberger , Katja Schmidt , Katja Metz , Christina Zwingmann , Norbert Brieske , Cindy Springer , Ana Martinez Hernandez , Sarah Herzog , Frauke Grabbe , Cornelia Sieverding , Barbara Fischer , Kathrin Schrader , Maren Brockmeyer , Sarah Dettmer , Christin Helbig , Violaine Alunni , Marie-Annick Battaini , Carole Mura , Charlotte N Henrichsen , Raquel Garcia-Lopez , Diego Echevarria , Eduardo Puelles , Elena Garcia-Calero , Stefan Kruse , Markus Uhr , Christine Kauck , Guangjie Feng , Nestor Milyaev , Chuang Kee Ong , Lalit Kumar , MeiSze Lam , Colin A Semple , Attila Gyenesei , Stefan Mundlos , Uwe Radelof , Hans Lehrach , Paolo Sarmientos , Alexandre Reymond , Duncan R Davidson , Pascal Dollé , Stylianos E Antonarakis , Marie-Laure Yaspo , Salvador Martinez , Richard A Baldock , Gregor Eichele , Andrea Ballabio |
2011-01-18 | - |
| 22087315 |
PLoS ONE Hongyu Wu , Lihe Chen , Qiaoling Zhou , Wenzheng Zhang |
2011-01-01 |
Scnn1a,
Dot1l,
Mllt6,
Mllt3
|
| 21170927 |
Widely expressed Af17 is likely not required for embryogenesis, hematopoiesis, and animal survival. Genesis Zhijing Zhang , Le Huang , Mary Rose Reisenauer , Hongyu Wu , Lihe Chen , Yujin Zhang , Yang Xia , Wenzheng Zhang |
2010-12-01 |
Gfap,
Mllt6,
Rbfox3
|
| 20412781 |
Dev. Cell Guoji Guo , Mikael Huss , Guo Qing Tong , Chaoyang Wang , Li Li Sun , Neil D Clarke , Paul Robson |
2010-04-20 |
Srcap,
Zbtb48,
Pds5b,
Dcun1d4,
Zfp513,
Zfp282,
Zfp956,
Zdhhc7,
Hinfp,
Zc3h10,
Etv5,
Isl2,
Rcor2,
Rhox9,
E2f4,
Mbnl2,
Cphx1,
Hmgxb3,
Ovol2,
Bmyc,
Jmjd6,
Gcm2,
Foxp1,
Ibtk,
Uhrf2,
Lmo1,
Cald1,
Dek,
Hivep1,
Lmx1a,
Lims1,
2610305D13Rik,
Foxp2,
Zbtb21,
Brdt,
Aebp2,
Nr0b1,
Ahr,
Aire,
Baz2a,
Mta3,
Ankfy1,
Nr2f2,
Klf16,
Arnt,
Arnt2,
Arntl,
Zfhx3,
Atf1,
Atf2,
Atf3,
Atf4,
Neurog3,
Bach1,
Bach2,
Bcl2l1,
Bcl3,
Prdm1,
Zfp36l1,
Zfp36l2,
Klf5,
Ctnnb1,
Runx2,
Runx3,
Cbx2,
Cdx1,
Cdx2,
Cdx4,
Cebpa,
Cited1,
Clock,
Creb3,
Atf6b,
Crem,
Crx,
Csrp1,
Csrp2,
Ctcf,
Cux1,
Cux2,
Dll1,
Dnmt1,
Dpm1,
Dr1,
Arid3a,
E2f1,
E2f5,
Ebf1,
Ebf3,
Phc1,
Egr1,
Ehf,
Elf1,
Elf3,
Elk1,
Epas1,
Nr2f1,
Erf,
Esr1
|
| 19864429 |
J Biol Chem Mary Rose Reisenauer , Marc Anderson , Le Huang , Zhijing Zhang , Qiaoling Zhou , Bruce C Kone , Andrew P Morris , Gene D Lesage , Stuart E Dryer , Wenzheng Zhang |
2009-12-18 | - |
| 18799693 |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. Gwenn M Hansen , Diane C Markesich , Michael B Burnett , Qichao Zhu , Karen M Dionne , Lizabeth J Richter , Richard H Finnell , Arthur T Sands , Brian P Zambrowicz , Alejandro Abuin |
2008-10-01 |
Gm11335,
Gm17762,
A930017K11Rik,
BC028777,
Gm13999,
Gm11696,
Gm12359,
Gm10589,
D030047H15Rik,
Gm10856,
Gm10685,
Gm10062,
Gm10433,
Gm10648,
Gm10840,
Gm15441,
Gm10684,
Gm9900,
Gm10822,
Gm10687,
Gm11744,
Gm10747,
Arih2os,
B230344G16Rik,
Fmr1os,
Tmem51os1,
Gm14488,
Gm13033,
Gm10789,
Gm10615,
Gm1976,
Gm9967,
Gm9917,
Gm1974,
Gm11496,
Gm13580,
Gm2085,
Gm2183,
Gm2245,
Tbx3os1,
Gm12980,
Gm2329,
Lncenc1,
Gm2381,
Snhg12,
Gm2479,
Gm12942,
Gm2529,
Gm2533,
Rpl30-ps7,
Rsf1os2,
Gm2695,
2810416G20Rik,
Rpl30-ps6,
Gm2773,
Gm2788,
Dynlt1f,
Gm9793,
Gm2885,
Gm2920,
Gm15506,
Gm11627,
Gm10518,
Gm13496,
Gm3134,
Gm12827,
Gm3143,
Gm10144,
Ahnak2,
Gm3196,
Gm13242,
Gm3325,
Gm13247,
Gm10863,
Gm13157,
4930522L14Rik,
Gm3552,
Gm15226,
Gm3604,
Gm3643,
BC005561,
Gm3716,
2810410L24Rik,
Gm10282,
Gm3839,
Nhsl2,
4732419C18Rik,
Gm3906,
Gm3973,
Gm4013,
Apol7d,
Gm12057,
Gm10489,
Rex2,
1110002L01Rik,
Gm4189,
Gm4204,
4632428C04Rik,
9130023H24Rik
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
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目前还没有研究热点人员