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24383 Gapdh

24383

Gapdh

glyceraldehyde-3-phosphate dehydrogenase

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition glyceraldehyde-3-phosphate dehydrogenase

研究结论

Date Results Publications
2017-08-12 11:01:00 Data (including data from studies in knockout mice) suggest that S100b acting as a humoral factor impairs glycolysis in muscle (myoblasts, myotubes, and skeletal muscles) independent of insulin action; this effect appears to be due to inhibition of Gapdh activity from enhanced poly(ADP-ribosyl)ation of Gapdh. (S100B = S100 protein, beta polypeptide, neural; Gapdh = glyceraldehyde-3-phosphate dehydrogenase) 28174179
2017-07-15 10:48:00 Study reveals GAPDH/Siah1 as a novel signaling pathway in apoptosis and function recovery after traumatic spinal cord injury. This signaling pathway in the spinal cord can be blocked by sivelestat sodium. 27256506
2016-12-17 11:53:00 In conclusion, the data show that two GAPDH binders could be therapeutically relevant in the treatment of injuries stemming from hard oxidative stress. 26748070
2016-12-17 10:09:00 psiGAPDH peptide is an inhibitor of the elimination of damaged mitochondria. 27129213
2015-08-29 10:49:00 The N terminus of nuclear GAPDH binds with and this complex promotes overactivation both in vitro and in vivo. 25882840

名称对应

Type IDs
Synonymous BARS-38, Gapd
Gene
UniProtKB-ID: G3P_RAT
UniprotKB: P04797
UniParc: UPI00000E6B8C
EMBL: M17701, M11561, AF106860, X02231, AB017801, BC087743, M29341, BC059110
Ensembl: ENSRNOG00000018630
KO: rno:108351137, rno:24383
Nucleutide sequences
EMBL-CDS: AAA40814.1, AAA41795.1, AAD08929.2, CAA26150.1, AAH59110.1, AAH87743.1, BAB11748.1, AAA41193.1
Ensembl_TRS: ENSRNOT00000050443
Protein sequencees
Ensembl_PRO: ENSRNOP00000040878
RefSeq: XP_017447924.1, NP_058704.1
Others
UniRef100: UniRef100_P04797
UniRef90: UniRef90_P04797
UniRef50: UniRef50_P04797
UniGene: Rn.91450, Rn.129558

全选

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研究热度

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